2-(2-吡啶基氨基)乙基二甲基胺合成路线 （共 20 条）
参考文献
Clark et al.
Journal of Organic Chemistry, 1949 , vol. 14, p. 216,220
参考文献
Kovacs; Vajda
Acta Chimica Academiae Scientiarum Hungaricae, 1959 , vol. 21, p. 445,450
Chemistry and Industry (London, United Kingdom), 1959 , p. 259
反应条件
1: SOCl2; pyridine
2: LiAlH4; diethyl ether
View Scheme
参考文献
Campaigne; Bourgeois
Journal of the American Chemical Society, 1954 , vol. 76, p. 2445
反应条件
sodium amide; toluene
参考文献
Campaigne; Le Suer
Journal of the American Chemical Society, 1949 , vol. 71, p. 333
反应条件
1: N,N-dimethyl-N'-(pyridine-2-yl)ethane-1,2-diamine With lithium amide in acetonitrile
0.0833333 h; Inert atmosphere;
2: benzyl halide in acetonitrile
8 h; Inert atmosphereReflux;
参考文献
Gogate, Priyanka N.; Ethirajan, Manivannan; Kurenova, Elena V.; Magis, Andrew T.; Pandey, Ravindra K.; Cance, William G.
European Journal of Medicinal Chemistry, 2014 , vol. 80, p. 154 - 156
反应条件
sodium hydride; toluene
参考文献
Biel
Journal of the American Chemical Society, 1949 , vol. 71, p. 1306,1307
反应条件
sodium amide; xylene
参考文献
Soc. Usines Chim. Rhone-Poulenc
Patent: DE880749 , 1951 ;
DRP/DRBP Org.Chem.
Full Text Show Details
Soc. Usines Chim. Rhone-Poulenc
Patent: US2502151 , 1946 ;
反应条件
1: N,N-dimethyl-N'-(pyridine-2-yl)ethane-1,2-diamine With lithium amide in acetonitrile
0.0833333 h; Inert atmosphere;
2: 4-bromobenzyl halide in acetonitrile
8 h; Inert atmosphereReflux;
参考文献
Gogate, Priyanka N.; Ethirajan, Manivannan; Kurenova, Elena V.; Magis, Andrew T.; Pandey, Ravindra K.; Cance, William G.
European Journal of Medicinal Chemistry, 2014 , vol. 80, p. 154 - 156
反应条件
sodium hydride; toluene
anschliessend mit 4-Fluor-benzylchlorid;
参考文献
Olah et al.
Acta Chimica Academiae Scientiarum Hungaricae, 1956 , vol. 8, p. 157,161
Full Text Show Details
Vaughan et al.
Journal of Organic Chemistry, 1949 , vol. 14, p. 228,232
反应条件
sodium amide; toluene
Behandeln des Reaktionsgemisches mit 3-Brom-benzylbromid;
参考文献
Vaughan et al.
Journal of Organic Chemistry, 1949 , vol. 14, p. 228,232
