甘氨酰-L-苯丙氨酰-L-丝氨酸合成路线 （共 4 条）
反应条件
piperidine in N,N-dimethyl-formamide T=50°C; 1 h; Microwave irradiation;
参考文献
El Khatib, Mirna; Elagawany, Mohamed; Jabeen, Farukh; Todadze, Ekaterina; Bol'Shakov, Oleg; Oliferenko, Alexander; Khelashvili, Levan; El-Feky, Said A.; Asiri, Abdullah; Katritzky, Alan R.
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 25 p. 4836 - 4838
反应条件
1: 10 palladium on activated charcoal; hydrogen / methanol / 4 h 2: piperidine / N,N-dimethyl-formamide / 1 h / 50 °C / Microwave irradiation View Scheme
参考文献
El Khatib, Mirna; Elagawany, Mohamed; Jabeen, Farukh; Todadze, Ekaterina; Bol'Shakov, Oleg; Oliferenko, Alexander; Khelashvili, Levan; El-Feky, Said A.; Asiri, Abdullah; Katritzky, Alan R.
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 25 p. 4836 - 4838
反应条件
1.1: thionyl chloride / dichloromethane / 0.25 h / 20 °C 1.2: 2.5 h / 20 °C 2.1: triethylamine / water; acetonitrile / 20 °C 3.1: N-ethyl-N,N-diisopropylamine / acetonitrile / 12 h / 20 °C 4.1: 10 palladium on activated charcoal; hydrogen / methanol / 4 h 5.1: N-ethyl-N,N-diisopropylamine / water; acetonitrile / 12 h / 20 °C 6.1: 10 palladium on activated charcoal; hydrogen / methanol / 4 h 7.1: piperidine / N,N-dimethyl-formamide / 1 h / 50 °C / Microwave irradiation View Scheme
参考文献
El Khatib, Mirna; Elagawany, Mohamed; Jabeen, Farukh; Todadze, Ekaterina; Bol'Shakov, Oleg; Oliferenko, Alexander; Khelashvili, Levan; El-Feky, Said A.; Asiri, Abdullah; Katritzky, Alan R.
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 25 p. 4836 - 4838
反应条件
1: triethylamine / water; acetonitrile / 20 °C 2: N-ethyl-N,N-diisopropylamine / acetonitrile / 12 h / 20 °C 3: 10 palladium on activated charcoal; hydrogen / methanol / 4 h 4: N-ethyl-N,N-diisopropylamine / water; acetonitrile / 12 h / 20 °C 5: 10 palladium on activated charcoal; hydrogen / methanol / 4 h 6: piperidine / N,N-dimethyl-formamide / 1 h / 50 °C / Microwave irradiation View Scheme
参考文献
El Khatib, Mirna; Elagawany, Mohamed; Jabeen, Farukh; Todadze, Ekaterina; Bol'Shakov, Oleg; Oliferenko, Alexander; Khelashvili, Levan; El-Feky, Said A.; Asiri, Abdullah; Katritzky, Alan R.
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 25 p. 4836 - 4838
