4-羟基-8-三氟甲基喹啉-3-甲酸乙酯合成路线 （共 7 条）
反应条件
dowtherm T=250°C; 5 h;
参考文献
Garudachari; Isloor, Arun M.; Satyanarayana; Fun, Hoong-Kun; Hegde, Gurumurthy
European Journal of Medicinal Chemistry, 2014 , vol. 74, p. 324 - 332
反应条件
1: 4 h / 110 °C 2: Dowtherm medium / 4 h / 250 °C View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 46, # 11 p. 5283 - 5292
反应条件
1: 4 h / 110 °C 2: Dowtherm medium / 4 h / 250 °C View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 46, # 11 p. 5283 - 5292
反应条件
1: T=120 - 150°C; 2: Heating;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 8 p. 1487 - 1490
参考文献
Hu, Baihua; Bernotas, Ron; Unwalla, Rayomand; Collini, Michael; Quinet, Elaine; Feingold, Irene; Goos-Nilsson, Annika; Wilhelmsson, Anna; Nambi, Ponnal; Evans, Mark; Wrobel, Jay
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 2 p. 689 - 693
反应条件
lithium hydroxide hydrate in methanol T=0°C; 2.16667 h;
参考文献
Garudachari; Isloor, Arun M.; Satyanarayana; Fun, Hoong-Kun; Hegde, Gurumurthy
European Journal of Medicinal Chemistry, 2014 , vol. 74, p. 324 - 332
反应条件
1: lithium hydroxide hydrate; methanol / 2 h / 0 °C
2: N-bromosuccinmide / tetrahydrofuran / 12 h / 20 °C
View Scheme
参考文献
Garudachari; Isloor, Arun M.; Satyanarayana; Fun, Hoong-Kun; Hegde, Gurumurthy
European Journal of Medicinal Chemistry, 2014 , vol. 74, p. 324 - 332
