1: ethyl magnesium chloride With titanium(IV) isopropylate in dichloromethane T=-78°C; 0.166667 h; Inert atmosphere; 2: benzaldehyde With (R)-3-(3,5-diphenylphenyl)-2,2'-dihydroxy-1,1'-binaphthyl in diethyl ether; dichloromethane T=0°C; 3 h; Inert atmosphere; 3: With hydrogenchloride; water in diethyl ether; dichloromethane T=0°C; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 83, # 1 p. 19 - 32
1: ortho-methylbenzoic acid With oxalyl dichloride; N,N-dimethyl-formamide in dichloromethane T=20°C; 0.333333 h; 2: ethyl magnesium chloride With iron (III) acetylacetonate in tetrahydrofuran T=20°C; 0.333333 h;
参考文献
Journal of the American Chemical Society, , vol. 127, # 28 p. 10028 - 10038
