1-(2-氯乙基)-2-咪唑啉酮合成路线 (共 14 条)
参考文献
US2840566 , ;
US2887485 , ;
Journal of the American Chemical Society, , vol. 78, p. 6144
Journal of the American Chemical Society, , vol. 79, p. 5276,5278
参考文献
Journal of the American Chemical Society, , vol. 78, p. 6144
Journal of the American Chemical Society, , vol. 79, p. 5276,5278
反应条件
potassium hydroxide; nickel monoaluminide in methanol degradation under various conditions (HBr in glac. CH3CO2H) with preparation of nonmutagenic reaction mixtures of products; Product distributionMechanism;
参考文献
Journal of Pharmaceutical Sciences, , vol. 78, # 8 p. 652 - 659
反应条件
potassium carbonate; potassium iodide in various solvent(s) 16 h; Heating;
参考文献
Perregaard; Arnt; Bogeso; Hyttel; Sanchez
Journal of Medicinal Chemistry, 1992 , vol. 35, # 6 p. 1092 - 1101
反应条件
potassium carbonate; potassium iodide in isobutyl methylketone 28 h; Inert atmosphereReflux;
参考文献
Sunil Kumar; Anjaneyulu; Hima Bindu
Beilstein Journal of Organic Chemistry, 2011 , vol. 7, p. 29 - 33
反应条件
ammonium hydroxide T=100°C;
参考文献
McKay et al.
Journal of the American Chemical Society, 1957 , vol. 79, p. 5276,5279
参考文献
McKay et al.
Journal of the American Chemical Society, 1957 , vol. 79, p. 5276,5279
反应条件
sodium carbonate in methanol; ethanol; ethyl acetate
参考文献
H. Lundbeck A/S
Patent: US4684650 A1, 1987 ;
反应条件
1: 65 percent / sodium carbonate, potassium iodide / 16 h / Heating 2: 86 percent / H2 / 5percent Pd/C / ethanol / 2 h / 155.1 Torr View Scheme
参考文献
Boegesoe, Klaus P.; Arnt, Joern; Boeck, Vita; Christensen, A. Vibeke; Hyttel, John; Jensen, Klaus Gundertofte
Journal of Medicinal Chemistry, 1988 , vol. 31, # 12 p. 2247 - 2256
反应条件
potassium carbonate; potassium iodide in various solvent(s) 16 h; Heating;
参考文献
Perregaard; Arnt; Bogeso; Hyttel; Sanchez
Journal of Medicinal Chemistry, 1992 , vol. 35, # 6 p. 1092 - 1101