4,7-二甲氧基-1H-吲哚合成路线 （共 16 条）
反应条件
tin(ll) chloride; ruthenium trichloride; triphenylphosphine in 1,4-dioxane T=180°C; 20 h;
参考文献
Cho, Chan Sik; Lim, Hyo Kyun; Shim, Sang Chul; Kim, Tae Jeong; Choi, Heung-Jin
Chemical Communications, 1998 , # 9 p. 995 - 996
反应条件
tin(ll) chloride; RuH2(PPh3)2 in 1,4-dioxane; water T=180°C; 20 h;
参考文献
Cho, Chan Sik; Kim, Jin Hwang; Kim, Tae-Jeong; Shim, Sang Chul
Tetrahedron, 2001 , vol. 57, # 16 p. 3321 - 3329
反应条件
1: AcOH; NaOAc / 5 h / Heating 2: H2; HCOONH4 / Pd/C / ethanol / 0.5 h / Heating View Scheme
参考文献
Showalter, H. D. Hollis; Pohlmann, Gerd
Organic Preparations and Procedures International, 1992 , vol. 24, # 4 p. 484 - 488
反应条件
quinoline; copper T=150 - 160°C; 3 h;
参考文献
Tapia, Ricardo A.; Prieto, Yolanda; Pautet, Felix; Walchshofer, Nadia; Fillion, Houda; Fenet, Bernard; Sarciron, Marie-Elizabeth
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 16 p. 3407 - 3412
反应条件
1: HNO3 / CH2Cl2 / 1 h / 0 - 5 °C 2: AcOH; NaOAc / 5 h / Heating 3: H2; HCOONH4 / Pd/C / ethanol / 0.5 h / Heating View Scheme
参考文献
Catrycke, Marc-Olivier; Houssin, Raymond; Henichart, Jean-Pierre; Pfeiffer, Bruno; Renard, Pierre; Dassonneville, Laurent; Bailly, Christian
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 14 p. 2025 - 2030
反应条件
PPA; Polyphosphoric acid (PPA) in xylene 1 h; Heating;
参考文献
Cherif, Mahmoud; Cotelle, Philippe; Catteau, Jean-Pierre
Heterocycles, 1992 , vol. 34, # 9 p. 1749 - 1758
反应条件
1: 90 percent / NaOH / H2O / 1 h / Heating 2: 95 percent / copper; quinoline / 3 h / 150 - 160 °C View Scheme
参考文献
Tapia, Ricardo A.; Prieto, Yolanda; Pautet, Felix; Walchshofer, Nadia; Fillion, Houda; Fenet, Bernard; Sarciron, Marie-Elizabeth
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 16 p. 3407 - 3412
反应条件
1: acetic acid / H2O / 3 h / 20 °C 2: CH2Cl2; toluene / 20 °C 3: 5.67 g / tetrabutylammonium fluoride / tetrahydrofuran / 1 h / 20 °C View Scheme
参考文献
Legentil, Laurent; Benel, Laurent; Bertrand, Viviane; Lesur, Brigitte; Delfourne, Evelyne
Journal of Medicinal Chemistry, 2006 , vol. 49, # 10 p. 2979 - 2988
反应条件
ammonium cerium(IV) nitrate in water; acetonitrile
1.5 h; Ambient temperature;
参考文献
Cherif, Mahmoud; Cotelle, Philippe; Catteau, Jean-Pierre
Heterocycles, 1992 , vol. 34, # 9 p. 1749 - 1758
反应条件
1: 95 percent / NaH / tetrahydrofuran / 0.5 h / 20 °C
2: 90 percent / CAN / acetonitrile; H2O / 0.5 h / 20 °C
3: 100 percent / TFA / CH2Cl2 / 2 h / 20 °C
View Scheme
参考文献
Legentil, Laurent; Bastide, Jean; Delfourne, Evelyne
Tetrahedron Letters, 2003 , vol. 44, # 12 p. 2473 - 2475
