2,2'-联噻吩-5,5'-二硼酸二(频哪醇)酯合成路线 （共 7 条）
反应条件
1: 2-(thien-2-yl)thiophene With AlCl3, aluminium chloride; boron trichloride; 4-(N,N-diethylamino)-toluene in dichloromethane 24 h; 2: 2,3-dimethylbutane-2,3-diol With triethylamine in dichloromethane T=20°C; 0.5 h;
参考文献
THE UNIVERSITY OF MANCHESTER; INGLESON, Michael James
Patent: WO2012/25760 A1, 2012 ;
Location in patent: Page/Page column 49-50 ;
反应条件
1: 2-(thien-2-yl)thiophene With n-butyllithium in tetrahydrofuran; hexane T=-78 - 20°C; 2 h; Inert atmosphere; 2: 2-isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane in tetrahydrofuran; hexane T=-78 - 20°C; Inert atmosphere;
参考文献
Li, Yaowen; Li, Zaifang; Wang, Chunyu; Li, Hui; Lu, Hongguang; Xu, Bin; Tian, Wenjing
Journal of Polymer Science, Part A: Polymer Chemistry, 2010 , vol. 48, # 13 p. 2765 - 2776
反应条件
1: 2-(thien-2-yl)thiophene With n-butyllithium in tetrahydrofuran T=-78 - 20°C; 4 h; 2: With boric acid trimethyl ester in tetrahydrofuran 2 h; 3: 2,3-dimethylbutane-2,3-diol in tetrahydrofuran 12 h; Further stages.;
参考文献
Journal of Organic Chemistry, , vol. 67, # 25 p. 8877 - 8884
反应条件
AlCl3; Me2NTol in dichloromethane 1:1 mixt. of BCl3 and AlCl, pinacol (2.3-3.0 equiv.) and lutidine (15 equiv.) for 18 h;
参考文献
Del Grosso, Alessandro; Helm, Matthew D.; Solomon, Sophia A.; Caras-Quintero, Dolores; Ingleson, Michael J.
Chemical Communications, 2011 , vol. 47, # 46 p. 12459 - 12461
反应条件
1: AlCl3, aluminium chloride; boron trichloride; 4-(N,N-diethylamino)-toluene / dichloromethane / 24 h / Inert atmosphere 2: triethylamine / 0.5 h / 20 °C / Inert atmosphere View Scheme
参考文献
Chemical Communications, , vol. 47, # 46 p. 12459 - 12461
反应条件
triethylamine T=20°C; 0.5 h; Inert atmosphere;
参考文献
Del Grosso, Alessandro; Helm, Matthew D.; Solomon, Sophia A.; Caras-Quintero, Dolores; Ingleson, Michael J.
Chemical Communications, 2011 , vol. 47, # 46 p. 12459 - 12461
反应条件
aluminum oxide; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium fluoride T=80°C; Suzuki coupling; 0.0333333 h; microwave irradiation;
参考文献
Melucci, Manuela; Barbarella, Giovanna; Sotgiu, Giovanna
Journal of Organic Chemistry, 2002 , vol. 67, # 25 p. 8877 - 8884
