1-乙酰基-1H-吲唑-5-羧酸甲酯合成路线 (共 4 条)
反应条件
1.1: sulfuric acid / 16 h / |Reflux 2.1: palladium 10 on activated carbon; ammonium formate / methanol / 3 h / 20 °C / |Inert atmosphere 3.1: potassium acetate / toluene / 0.17 h / |Inert atmosphere; |Reflux 3.2: 16.5 h / |Reflux; |Inert atmosphere View Scheme
参考文献
Hawes, Chris S.; Babarao, Ravichandar; Hill, Matthew R.; White, Keith F.; Abrahams, Brendan F.; Kruger, Paul E.
Chemical Communications, 2012 , vol. 48, # 94 p. 11558 - 11560
反应条件
1.1: palladium 10 on activated carbon; ammonium formate / methanol / 3 h / 20 °C / |Inert atmosphere 2.1: potassium acetate / toluene / 0.17 h / |Inert atmosphere; |Reflux 2.2: 16.5 h / |Reflux; |Inert atmosphere View Scheme
参考文献
Hawes, Chris S.; Babarao, Ravichandar; Hill, Matthew R.; White, Keith F.; Abrahams, Brendan F.; Kruger, Paul E.
Chemical Communications, 2012 , vol. 48, # 94 p. 11558 - 11560
反应条件
1: With potassium acetate in toluene 0.166667 h; Inert atmosphereReflux; 2: With isopentyl nitrite in toluene 16.5 h; RefluxInert atmosphere;
参考文献
Hawes, Chris S.; Babarao, Ravichandar; Hill, Matthew R.; White, Keith F.; Abrahams, Brendan F.; Kruger, Paul E.
Chemical Communications, 2012 , vol. 48, # 94 p. 11558 - 11560
反应条件
1: With lithium hydroxide hydrate in tetrahydrofuran; water 48 h; Reflux; 2: With hydrogenchloride in water pH=4;
参考文献
Hawes, Chris S.; Babarao, Ravichandar; Hill, Matthew R.; White, Keith F.; Abrahams, Brendan F.; Kruger, Paul E.
Chemical Communications, 2012 , vol. 48, # 94 p. 11558 - 11560