2-氟-4-三氟甲基苯乙腈合成路线 （共 3 条）
反应条件
1: With N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate in dimethyl sulfoxide T=90°C; 20 h; Inert atmosphere; 2: With water; sodium chloride T=107°C; Krapcho decarboxylation; 18 h; Inert atmosphere;
参考文献
Stazi, Federica; Maton, William; Castoldi, Damiano; Westerduin, Pieter; Curcuruto, Ornella; Bacchi, Sergio
Synthesis, 2010 , # 19 art. no. T09110SS, p. 3332 - 3338
反应条件
thionyl chloride in tetrahydrofuran T=20°C;
参考文献
Stazi, Federica; Maton, William; Castoldi, Damiano; Westerduin, Pieter; Curcuruto, Ornella; Bacchi, Sergio
Synthesis, 2010 , # 19 art. no. T09110SS, p. 3332 - 3338
反应条件
water; sodium chloride in dimethyl sulfoxide T=110°C; Krapcho decarboxylation;
参考文献
Stazi, Federica; Maton, William; Castoldi, Damiano; Westerduin, Pieter; Curcuruto, Ornella; Bacchi, Sergio
Synthesis, 2010 , # 19 art. no. T09110SS, p. 3332 - 3338
