1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -42 °C / Inert atmosphere 1.2: 0.5 h / Inert atmosphere 2.1: silver(I) acetate; palladium diacetate; dimethyl sulfoxide; p-benozquinone / 1,4-dioxane / 48 h / 130 - 140 °C 3.1: silver(I) acetate; palladium diacetate / 1,4-dioxane / 1 h / 140 °C View Scheme

1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -42 °C / Inert atmosphere 1.2: 0.5 h / Inert atmosphere 2.1: palladium diacetate / dichloromethane / 4 h / 65 - 70 °C 2.2: 4 h / 110 °C View Scheme

1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -42 °C / Inert atmosphere 1.2: 0.5 h / Inert atmosphere 2.1: silver(I) acetate; palladium diacetate; dimethyl sulfoxide; p-benozquinone / 1,4-dioxane / 48 h / 130 - 140 °C View Scheme

copper(l) iodide; potassium carbonate; N-methyl-2-(methylamino)ethylamine in acetonitrile T=80°C; 24 h; Inert atmosphere;