2-氨基-4-(苄氧基)-3-甲氧基苯甲酸合成路线 （共 2 条）
参考文献
Su; Kohler; Chou; Moon Woo Chun; Watanabe
Journal of Medicinal Chemistry, 1992 , vol. 35, # 14 p. 2703 - 2710
反应条件
1: 60 percent / Cu, Cu2O, K2CO3 / bis-(2-methoxy-ethyl) ether / 5 h / Heating
2: SOCl2, pyridine / benzene / 0.17 h / 0 °C
3: 1.) piperidine, Et3N, 2.) POCl3 / 1.) CHCl3, RT, 20 min, 2.) 100 deg C, 30 min
4: 96 percent / K2CO3 / acetone / 16 h / Heating
5: 54 percent / BBr3 / CH2Cl2 / a) -78 deg C, 0.5 h, b) -78 to -20 deg C, 10 min
View Scheme
参考文献
Su, Tsann-Long; Dziewiszek, Krzysztof; Wu, Tian-Shung
Tetrahedron Letters, 1991 , vol. 32, # 12 p. 1541 - 1544
