1,2-二(2-噻吩基)乙炔合成路线 （共 26 条）
反应条件
sodium hydroxide; copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); N-benzyl-N,N,N-triethylammonium chloride in benzene
T=40°C; 48 h;
参考文献
D'Auria
Synthetic Communications, 1992 , vol. 22, # 16 p. 2393 - 2399
反应条件
C91H89MoO16Si4(1-)*K(1+) in toluene
T=50°C; Inert atmosphereMolecular sieve;
参考文献
Heppekausen, Johannes; Stade, Robert; Kondoh, Azusa; Seidel, Guenter; Goddard, Richard; Fuerstner, Alois
Chemistry - A European Journal, 2012 , vol. 18, # 33 p. 10281 - 10299
反应条件
water; 1,8-diazabicyclo[5.4.0]undec-7-ene; triphenylphosphine; Pd-Ni in toluene
T=80°C; Sonogashira coupling; 18 h;
参考文献
Son, Seung Uk; Jang, Youngjin; Park, Jongnam; Na, Hyon Bin; Park, Hyun Min; Yun, Hyung Joong; Lee, Jouhahn; Hyeon, Taeghwan
Journal of the American Chemical Society, 2004 , vol. 126, # 16 p. 5026 - 5027
反应条件
copper(l) iodide; palladium diacetate; triethylamine; triphenylphosphine in acetonitrile
T=20°C; Sonogashira coupling; Inert atmosphere;
参考文献
Chuentragool, Padon; Vongnam, Kunnigar; Rashatasakhon, Paitoon; Sukwattanasinitt, Mongkol; Wacharasindhu, Sumrit
Tetrahedron, 2011 , vol. 67, # 42 p. 8177 - 8182
反应条件
bis-triphenylphosphine-palladium(II) chloride; octadecyl-trimethylammonium chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,4-di(diphenylphosphino)-butane in water
12 h; Heating;
参考文献
Park, Kyungho; Bae, Goun; Park, Ahbyeol; Kim, Yong; Choe, Jaehoon; Song, Kwang Ho; Lee, Sunwoo
Tetrahedron Letters, 2011 , vol. 52, # 5 p. 576 - 580
反应条件
piperidine; caesium carbonate; [(P{(C6H11)3})2Pd(Cl)2] in dimethyl sulfoxide
T=120°C; Sonogashira coupling; 12 h;
参考文献
Yi, Chenyi; Hua, Ruimao; Zeng, Hanxiang; Huang, Qiufeng
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 10 p. 1738 - 1742
反应条件
NW(OC(CF3)2Me)3(DME) in toluene
T=95°C; 11 h; Inert atmosphere;
参考文献
Geyer, Andrea M.; Wiedner, Eric S.; Gary, J. Brannon; Gdula, Robyn L.; Kuhlmann, Nicola C.; Johnson, Marc J. A.; Dunietz, Barry D.; Kampf, Jeff W.
Journal of the American Chemical Society, 2008 , vol. 130, # 28 p. 8984 - 8999
反应条件
triethylamine; copper(l) iodide in N,N-dimethyl-formamide
T=30°C; 12 h;
参考文献
Pal, Manojit; Kundu, Nitya G.
Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 5 p. 449 - 451
反应条件
dichloro bis(acetonitrile) palladium(II) in N,N-dimethyl-formamide
T=25°C; heteroarylation; 16 h;
参考文献
Ng; Novak; Wang; Huang
Tetrahedron, 1997 , vol. 53, # 39 p. 13339 - 13350
反应条件
potassium hydroxide; 18-crown-6 ether; 1,4-di(diphenylphosphino)-butane; palladium diacetate in toluene
T=100°C; 48 h;
参考文献
Abele, Edgars; Abele, Ramona; Arsenyan, Pavel; Lukevics, Edmunds
Tetrahedron Letters, 2003 , vol. 44, # 20 p. 3911 - 3913
