乙基2-[(4-乙氧基苯基)磺酰基]丙酸酯合成路线 （共 4 条）
反应条件
Oxonereg; in tetrahydrofuran; methanol T=20°C;
参考文献
Wyeth Holdings Corporation
Patent: EP970046 B1, 2003 ;
Location in patent: Page 26 ;
反应条件
1: 98 percent / 18-crown-6; K2CO3 / acetone / 8 h / Heating 2: aq. Oxone / methanol; tetrahydrofuran / 20 °C View Scheme
参考文献
Aranapakam, Venkatesan; Grosu, George T.; Davis, Jamie M.; Hu, Baihua; Ellingboe, John; Baker, Jannie L.; Skotnicki, Jerauld S.; Zask, Arie; DiJoseph, John F.; Sung, Amy; Sharr, Michele A.; Killar, Loran M.; Walter, Thomas; Jin, Guixian; Cowling, Rebecca
Journal of Medicinal Chemistry, 2003 , vol. 46, # 12 p. 2361 - 2375
反应条件
1: 99 percent / Et3N / acetone; CHCl3 / 1 h / Heating 2: 98 percent / 18-crown-6; K2CO3 / acetone / 8 h / Heating 3: aq. Oxone / methanol; tetrahydrofuran / 20 °C View Scheme
参考文献
Aranapakam, Venkatesan; Grosu, George T.; Davis, Jamie M.; Hu, Baihua; Ellingboe, John; Baker, Jannie L.; Skotnicki, Jerauld S.; Zask, Arie; DiJoseph, John F.; Sung, Amy; Sharr, Michele A.; Killar, Loran M.; Walter, Thomas; Jin, Guixian; Cowling, Rebecca
Journal of Medicinal Chemistry, 2003 , vol. 46, # 12 p. 2361 - 2375
反应条件
1: 99 percent / Et3N / acetone; CHCl3 / 1 h / Heating 2: 98 percent / 18-crown-6; K2CO3 / acetone / 8 h / Heating 3: aq. Oxone / methanol; tetrahydrofuran / 20 °C View Scheme
参考文献
Aranapakam, Venkatesan; Grosu, George T.; Davis, Jamie M.; Hu, Baihua; Ellingboe, John; Baker, Jannie L.; Skotnicki, Jerauld S.; Zask, Arie; DiJoseph, John F.; Sung, Amy; Sharr, Michele A.; Killar, Loran M.; Walter, Thomas; Jin, Guixian; Cowling, Rebecca
Journal of Medicinal Chemistry, 2003 , vol. 46, # 12 p. 2361 - 2375
