反应条件
1: 1.) Mg / 1.) THF, 2.) THF, r.t., 2 h 2: 96 percent / hydroxylamine hydrochloride, pyridine / ethanol / 12 h / 60 °C 3: Et3N, (N,N-dimethylamino)pyridine / CH2Cl2 / 0.75 h / Ambient temperature 4: liq. NH3 / CH2Cl2 / 18 h / Ambient temperature 5: 77 percent / tert-butyl hypochlorite, Et3N / ethanol; 2-methyl-propan-2-ol / 2 h / Ambient temperature 6: 1.) thallium(III) trifluoroacetate, 2.) PdCl2, LiCl, MgO / 1.) TFA, r.t., 24 h, 2.) r.t., 43 h 7: 98 percent / BBr3 / CH2Cl2 / 0.5 h / 0 °C View Scheme
参考文献
Hatanaka, Yasumaru; Hashimoto, Makoto; Kurihara, Hiroko; Nakayama, Hitoshi; Kanaoka, Yuichi
Journal of Organic Chemistry, 1994 , vol. 59, # 2 p. 383 - 387
