2-(6-甲氧基-2-萘基)丙酸合成路线 (共 130 条)
反应条件
sodium hydroxide in ethanol T=65°C; Hydrolysis; Kinetics; Further Variations:pH-valuesReagents;
参考文献
Pharmazie, , vol. 54, # 11 p. 831 - 836
反应条件
water; 1,3,4,6,7,8-hexahydro-1-methyl-2H-pyrimido{1,2-a}pyrimidine in 2,2,4-trimethylpentane Kinetics; Further Variations:Solventsreagent ratio;
参考文献
Journal of Physical Organic Chemistry, , vol. 17, # 5 p. 387 - 392
反应条件
in diethyl ether; toluene Yields of byproduct given;
参考文献
Chemistry Letters, , p. 1431 - 1434
反应条件
sodium hydride in N,N-dimethyl-formamide T=-60 - 20°C; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the Chemical Society, Chemical Communications, , # 10 p. 768 - 769
反应条件
in phosphate buffer T=37°C; Hydrolysis; pH=7.4; Kinetics; Further Variations:Reaction partners;
参考文献
Journal of Pharmaceutical Sciences, , vol. 87, # 12 p. 1622 - 1628
反应条件
in phosphate buffer T=37°C; Hydrolysis; pH=7.4; Kinetics; Further Variations:Reaction partners;
参考文献
Journal of Pharmaceutical Sciences, , vol. 87, # 12 p. 1622 - 1628
反应条件
(i) TsOH, EtOH, (ii) KOH; Multistep reaction;
参考文献
Tetrahedron, , vol. 34, # 20 p. 3081 - 3088
反应条件
phosphate buffer T=37°C; t 1/2= 42 h;
参考文献
Tetrahedron Letters, , vol. 35, # 38 p. 7107 - 7110
反应条件
ammonium cerium(IV) nitrate in methanol 0.5 h; var. molar ratio of the oxidant; other oxidant; also anodic oxidation; sodium salt of naproxen; Product distribution;
参考文献
Bosca; Martinez-Manez; Miranda; Primo; Soto; Vano
Journal of Pharmaceutical Sciences, 1992 , vol. 81, # 5 p. 479 - 482
参考文献
Harrison; Lewis; Nelson; Rooks; Roszkowski; Tomolonis; Fried
Journal of medicinal chemistry, 1970 , vol. 13, # 2 p. 203 - 205