2-(6-甲氧基-2-萘基)丙酸合成路线 （共 130 条）
参考文献
The Boots Company Limited
Patent: US3959364 A1, 1976 ;
参考文献
Noorduin, Wim L.; Kaptein, Bernard; Meekes, Hugo; Enckevort, Willem J. P. van; Kellogg, Richard M.; Vlieg, Elias
Angewandte Chemie, International Edition, 2009 , vol. 48, p. 4581 - 4583
Angewandte Chemie, 2009 , vol. 121, p. 4651 - 4653
反应条件
Saccharomyces cerevisiae wild type strain V328 0.333333 h; UV-irradiation;
参考文献
Bracchitta, Giuseppina; Catalfo, Alfio; De Guidi, Guido
Photochemical and Photobiological Sciences, 2013 , vol. 12, # 6 p. 967 - 973
反应条件
Saccharomyces cerevisiae wild type strain V328 0.333333 h; UV-irradiation;
参考文献
Photochemical and Photobiological Sciences, , vol. 12, # 6 p. 967 - 973
反应条件
1: With hydrogen bromide in water; acetic acid T=150°C; 3 h; 2: With water 0.5 h;
参考文献
Auspex Pharmaceuticals, Inc.
Patent: US2007/276042 A1, 2007 ;
Location in patent: Page/Page column 58 ;
US 20070276042 A1
反应条件
ammonium cerium(IV) nitrate in methanol 0.5 h; var. molar ratio of the oxidant; other oxidant; also anodic oxidation; sodium salt of naproxen; Product distribution;
参考文献
Bosca; Martinez-Manez; Miranda; Primo; Soto; Vano
Journal of Pharmaceutical Sciences, 1992 , vol. 81, # 5 p. 479 - 482
反应条件
1: With hydrogen bromide in water; acetic acid T=150°C; 3 h; 2: With water 0.5 h;
参考文献
Auspex Pharmaceuticals, Inc.
Patent: US2007/276042 A1, 2007 ;
Location in patent: Page/Page column 58 ;
US 20070276042 A1
反应条件
sodium hydroxide in water; toluene
参考文献
Albemarle Corporation
Patent: US5874614 A1, 1999 ;
反应条件
sodium hydroxide in toluene
参考文献
Albemarle Corporation
Patent: US5936118 A1, 1999 ;
反应条件
(+)-(S)-α-Np-BTM; 4-methoxybenzoic anhydride; N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C; 12 h; Resolution of racemate; optical yield given as percent ee;
参考文献
Shiina, Isamu; Nakata, Kenya; Ono, Keisuke; Onda, Yu-Suke; Itagaki, Makoto
Journal of the American Chemical Society, 2010 , vol. 132, # 33 p. 11629 - 11641
