2-(6-甲氧基-2-萘基)丙酸合成路线 （共 130 条）
反应条件
chromic acid Yield given;
参考文献
Chemistry Letters, , p. 341 - 344
反应条件
methyloxirane in water; acetone IrradiationpH neutral;
参考文献
Tetrahedron, , vol. 50, # 4 p. 1243 - 1260
反应条件
lithium aluminium tetrahydride; TiI4 in tetrahydrofuran T=-5°C; 0.5 h;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 13 p. 1771 - 1774
反应条件
(i) EtOH, H2SO4, (ii) /BRN= 969135/, NaH, 1,2-dimethoxy-ethane, (iii) KOH, EtOH; Multistep reaction;
参考文献
Journal of medicinal chemistry, , vol. 13, # 2 p. 203 - 205
反应条件
1: 547 mg / H2 / Pd/C / ethyl acetate / 2 h / 2206.5 Torr 2: 94 percent / KOH, EtOH / 4 h / Heating View Scheme
参考文献
Synthetic Communications, , vol. 14, # 14 p. 1365 - 1372
反应条件
1.1: n-butyllithium; N,N,N'-trimethyl-ethylenediamine / tetrahydrofuran; hexane / 0.75 h / -20 °C / Inert atmosphere 1.2: 1.83 h / -20 - 30 °C / Inert atmosphere 2.1: 9,10-dimethyl-9,10-dibora-9,10-dihydroanthracene / tetrahydrofuran / 0.08 h 2.2: 16 h / 60 °C 3.1: sodium hydroxide / tetrahydrofuran; water / 24 h / 65 °C View Scheme
参考文献
Organic Letters, , vol. 14, # 13 p. 3268 - 3271
反应条件
1: 93 percent / tetrakis(tri-p-tolyl phosphite)nickel(0), tri-p-tolyl phosphite, ionol / toluene 2: 85 percent / KOH, H2O / ethane-1,2-diol / 24 h / 125 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 50, # 25 p. 5370 - 5372
反应条件
1: 1.) borane-dimethyl sulfide, 2.) H2O2/NaOH 2: O2 / Pd View Scheme
参考文献
Tetrahedron Letters, , vol. 33, # 46 p. 6919 - 6922
反应条件
1: 1.) boron trifluoride etherate/molecular sieve 4A / 1.) benzene, reflux, 50 h; 2.) THF, RT, 1 h; 40 deg C, 1 h; reflux, 2 h 2: 71 percent / potassium hydroxide / ethane-1,2-diol / 8 h / Heating View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 31, # 9 p. 3139 - 3148
