2-甲氧基-5-(三氟甲基)苯硼酸合成路线 (共 4 条)
反应条件
1: With n-butyllithium in tetrahydrofuran; cyclohexane T=-30°C; 2: With tri-isopropoxy-borane in tetrahydrofuran; cyclohexane T=-70 - 20°C;
参考文献
Audouze, Karine; Nielsen, Elsebet stergaard.; Peters, Dan
Journal of Medicinal Chemistry, 2004 , vol. 47, # 12 p. 3089 - 3104
反应条件
sodium in methanol; water
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 1 h; 2: With triisopropyl borate 3: With hydrogenchloride in water; ethyl acetate
参考文献
Journal of Medicinal Chemistry, , vol. 56, # 17 p. 6626 - 6637
反应条件
dihydrogen peroxide in ethanol 2.5 h; Heating;
参考文献
Audouze, Karine; Nielsen, Elsebet stergaard.; Peters, Dan
Journal of Medicinal Chemistry, 2004 , vol. 47, # 12 p. 3089 - 3104