反应条件
1: With 2,2,6,6-tetramethyl-piperidine; n-butyllithium in diethyl ether; hexane T=-78°C; 0.75 h; Inert atmosphere; 2: With iodine in diethyl ether; hexane T=-78 - 20°C; Inert atmosphere;
参考文献
Trabanco, Andres A.; Tresadern, Gary; MacDonald, Gregor J.; Vega, Juan Antonio; De Lucas, Ana Isabel; Matesanz, Encarnacion; Garcia, Aranzazu; Linares, Maria Lourdes; Alonso De Diego, Sergio A.; Alonso, Jose Manuel; Oehlrich, Daniel; Ahnaou, Abdelah; Drinkenburg, Wilhelmus; MacKie, Claire; Andres, Jose Ignacio; Lavreysen, Hilde; Cid, Jose Maria
Journal of Medicinal Chemistry, 2012 , vol. 55, # 6 p. 2688 - 2701