5,6-二甲氧基-1,2,3,4-四氢1-萘酮合成路线 （共 26 条）
反应条件
1: ZnI2 / benzene / 5 h / 60 °C
2: LiAlH4 / benzene; diethyl ether / 2 h / Heating
View Scheme
参考文献
DeBernardis; Kerkman; Winn; Bush; Arendsen; McClellan; Kyncl; Basha
Journal of Medicinal Chemistry, 1985 , vol. 28, # 10 p. 1398 - 1404
反应条件
hydrogenchloride; aluminium trichloride in methanol; benzene
参考文献
ABBOTT LABORATORIES
Patent: EP166937 B1, 1991 ;
反应条件
1: ZnI2
2: HCl / ethanol
View Scheme
参考文献
DeBernardis; Kerkman; Winn; Bush; Arendsen; McClellan; Kyncl; Basha
Journal of Medicinal Chemistry, 1985 , vol. 28, # 10 p. 1398 - 1404
反应条件
aluminium trichloride in toluene
参考文献
Abbott Laboratories
Patent: US5128362 A1, 1992 ;
反应条件
aluminium trichloride in benzene
参考文献
Zhang; Yao; Hua; Van Breemen; Bolton
Chemical Research in Toxicology, 2001 , vol. 14, # 6 p. 754 - 763
反应条件
1: NaBH4 / aq. ethanol
2: KHSO4
3: (i) MCPBA, CHCl3, (ii) aq. HCl, EtOH
View Scheme
参考文献
Cannon; O'Donnell; Rosazza; Hoppin
Journal of Medicinal Chemistry, 1974 , vol. 17, # 5 p. 565 - 568
