6-甲基-2,4-二氧代-1,2,3,4-四氢-嘧啶-5-甲醛合成路线 （共 3 条）
反应条件
dipotassium peroxodisulfate; silver nitrate in water 1.) 90-100 deg C; 2.) room temp. 16 h;
参考文献
Ottenheijm, Harry C.J.; Liskamp, Rob M.J.; Nispen, Simon P.J.M. van; Boots, Hans A.; Tijhuis, Marian W.
Journal of Organic Chemistry, 1981 , vol. 46, # 16 p. 3273 - 3283
反应条件
nach Reimer-Tiemann;
参考文献
Journal of the Chemical Society, , p. 4845,4850
反应条件
1: 40 percent / dimethylformamide / 96 h / Ambient temperature
2: 90 percent / NaOH / methanol; dioxane; H2O / 16 h / 40 °C
3: 1.) Triethylamine; 2.) Hydroxybenztriazole, DCC / DMF, room temp., 16 h
4: 63 percent / LiBH4 / 1,2-dimethoxy-ethane / 1.) -78 deg C; 2.) room temp., 2 h
View Scheme
参考文献
Ottenheijm, Harry C.J.; Liskamp, Rob M.J.; Nispen, Simon P.J.M. van; Boots, Hans A.; Tijhuis, Marian W.
Journal of Organic Chemistry, 1981 , vol. 46, # 16 p. 3273 - 3283
