3-溴-1,8-萘二甲酸酐合成路线 （共 13 条）
反应条件
1.1: aq. NaOH
1.2: HgO; glacial AcOH / 96 h / Heating
1.3: 5M aq. HCl / 4 h / Heating
2.1: (COCl)2; DMF / CH2Cl2
3.1: pyridine / dimethylformamide / 180 °C
View Scheme
参考文献
Moseley, Jonathan D.; Moss, William O.; Welham, Matthew J.; Ancell, Claire L.; Banister, John; Bowden, Sharon A.; Norton, Glenn; Young, Maureen J.
Organic Process Research and Development, 2003 , vol. 7, # 1 p. 58 - 66
反应条件
water; acetic acid; sodium hydroxide
96 h; Reflux;
参考文献
GREEN CROSS CORPORATION; LEE, Jinhwa; KIM, Jeongmin; LEE, Suk Ho; LEE, Junwon; SONG, Kwang-Seop; PARK, Eun-Jung; KIM, Min Ju; SEO, Hee Jeong; LEE, Sung-Han; SON, Eun Jung; KIM, Jong Yup; KANG, Suk Youn; KONG, Younggyu
Patent: WO2011/159067 A2, 2011 ;
Location in patent: Page/Page column 54 ;
WO 2011/159067 A2
反应条件
1.1: aq. NaOH
1.2: HgO; glacial AcOH / 96 h / Heating
1.3: 5M aq. HCl / 4 h / Heating
2.1: (COCl)2; DMF / CH2Cl2
3.1: pyridine / dimethylformamide / 180 °C
4.1: aq. LiOH / tetrahydrofuran; methanol
View Scheme
参考文献
Moseley, Jonathan D.; Moss, William O.; Welham, Matthew J.; Ancell, Claire L.; Banister, John; Bowden, Sharon A.; Norton, Glenn; Young, Maureen J.
Organic Process Research and Development, 2003 , vol. 7, # 1 p. 58 - 66
