2-(4-硝基苯基氨基)吡啶合成路线 （共 7 条）
反应条件
potassium hydroxide in dimethyl sulfoxide T=20 - 100°C; 15 h;
参考文献
F2G LTD
Patent: WO2006/123145 A1, 2006 ;
Location in patent: Page/Page column 57 ;
反应条件
aluminum oxide; tris-(dibenzylideneacetone)dipalladium(0); potassium carbonate in neat (no solvent) T=140°C; 0.333333 h; Microwave irradiationGreen chemistry;
参考文献
Basolo, Luca; Bernasconi, Alice; Broggini, Gianluigi; Gazzola, Silvia; Beccalli, Egle M.
Synthesis (Germany), 2013 , vol. 45, # 22 art. no. SS-2013-Z0383-OP, p. 3151 - 3156
反应条件
cesium fluoride in acetonitrile T=20°C; Inert atmosphere;
参考文献
Fang, Yuesi; Larock, Richard C.
Tetrahedron, 2012 , vol. 68, # 13 p. 2819 - 2826
反应条件
1: With potassium carbonate in 1-methyl-pyrrolidin-2-one T=60°C; 1 h; 2: With potassium tert-butylate in 1-methyl-pyrrolidin-2-one 6 h;
参考文献
L'Oreal S.A.
Patent: US7329288 B2, 2008 ;
Location in patent: Page/Page column 13 ;
反应条件
potassium tert-butylate in ammonia T=-70°C; 0.5 h;
参考文献
Iwasaki, Genji; Saeki, Seitaro; Hamana, Masatomo
Chemistry Letters, 1986 , p. 31 - 34
反应条件
potassium tert-butylate; palladium diacetate; bis[2-(diphenylphosphino)phenyl] ether in toluene T=100°C; Inert atmosphere;
参考文献
Chu, Jean-Ho; Wu, Chung-Chiu; Chang, Deng-Hsiang; Lee, Ya-Ming; Wu, Ming-Jung
Organometallics, 2013 , vol. 32, # 1 p. 272 - 282
反应条件
tris-(dibenzylideneacetone)dipalladium(0); caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl in N,N-dimethyl-formamide T=80°C; 18 h;
参考文献
Burgeson, James R.; Moore, Amy L.; Boutilier, Jordan K.; Cerruti, Natasha R.; Gharaibeh, Dima N.; Lovejoy, Candace E.; Amberg, Sean M.; Hruby, Dennis E.; Tyavanagimatt, Shanthakumar R.; Allen III, Robert D.; Dai, Dongcheng
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 13 p. 4263 - 4272
