4'-溴-2'-甲基乙酰苯胺合成路线 （共 43 条）
参考文献
Joshi; Gupta
Journal of the Indian Chemical Society, 1959 , vol. 36, p. 329,333
反应条件
1: 87 percent / Na2CO3 / Pd(PPh3)4 / 80 °C 2: 97 percent / 2 M HCl / Heating View Scheme
参考文献
Mikami, Masafumi; Shinkai, Seiji
Journal of the Chemical Society, Chemical Communications, 1995 , # 2 p. 153 - 154
反应条件
1: nitration 2: H2 / Raney nickel View Scheme
参考文献
Gupta, G. D.; Gupta, Rakesh P.; Pujari, H. K.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 12 p. 1035 - 1037
反应条件
potassium permanganate; water Verseifen des Produkts mit konz. Salzsaeure;
参考文献
Boettcher, Stephan; Thiem, Joachim
European Journal of Organic Chemistry, 2014 , vol. 2014, # 3 p. 564 - 574
反应条件
1: With hydrogenchloride in ethanol; water 3 h; Reflux; 2: With sodium hydroxide in water T=20°C; 0.5 h;
参考文献
GRUeNENTHAL GMBH; FRANK, Robert; BAHRENBERG, Gregor; CHRISTOPH, Thomas; SCHIENE, Klaus; DE VRY, Jean; DAMANN, Nils; FRORMANN, Sven; LESCH, Bernhard; LEE, Jeewoo; KIM, Yong-Soo; KIM, Myeong-Seop
Patent: WO2010/127855 A1, 2010 ;
Location in patent: Page/Page column 118; 119 ;
参考文献
Fujio,M. et al.
Bulletin of the Chemical Society of Japan, 1975 , vol. 48, p. 2127 - 2133
反应条件
0.60mol Pd/C; hydrogen; sodium hydrogencarbonate in methanol T=20°C; 0.833333 h; regioselective reaction;
参考文献
Synthesis, , # 2 art. no. M04609SS, p. 217 - 220
反应条件
1: concentrated hydrochloric acid; sodium chlorate / nachfolgende Verseifung 3: fuming nitric acid / <5 4: tin; hydrochloric acid View Scheme
参考文献
Cohen; Murray
Journal of the Chemical Society, 1915 , vol. 107, p. 849
反应条件
1: nitration
2: H2 / Raney nickel
3: 72 percent
View Scheme
参考文献
Gupta, G. D.; Gupta, Rakesh P.; Pujari, H. K.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 12 p. 1035 - 1037
反应条件
{C6H3[NHP(piperidinyl)2]2Pd(Cl)}; potassium carbonate in 1,4-dioxane; water; butan-1-ol
T=100°C; Suzuki-Miyaura reaction; 5 h;
参考文献
Bolliger, Jeanne L.; Frech, Christian M.
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 6 p. 1075 - 1080
