2-溴-3,6-二羟基苯甲醛合成路线 （共 5 条）
反应条件
bromine in chloroform Inert atmosphere;
参考文献
Wang, Zhang; Dai, Mingji; Park, Peter K.; Danishefsky, Samuel J.
Tetrahedron, 2011 , vol. 67, # 52 p. 10249 - 10260
反应条件
1: 97 percent / BBr3 / CH2Cl2 / 1 h / -78 - 0 °C 2: Br2 / CHCl3 / 20 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 125, # 17 p. 5095 - 5106
反应条件
1H-imidazole in dichloromethane T=20°C; 0.25 h;
参考文献
Goddard, Mary-Lorene; Tabacchi, Raffaele
Tetrahedron Letters, 2006 , vol. 47, # 6 p. 909 - 911
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=20°C; 1.5 h;
参考文献
Takao, Ken-Ichi; Nanamiya, Ryuki; Fukushima, Yuuki; Namba, Ayumi; Yoshida, Keisuke; Tadano, Kin-Ichi
Organic Letters, 2013 , vol. 15, # 21 p. 5582 - 5585
反应条件
1: 80 percent / i-Pr2EtN / CH2Cl2 / 1 h / 20 °C
2: 79 percent / cuprous iodide; bis(triphenylphosphine) palladium dichloride; triethylamine / dimethylformamide / 3 h / 60 °C
3: 60 percent / TFA / CH2Cl2 / 6 h / 0 °C
View Scheme
参考文献
Goddard, Mary-Lorene; Tabacchi, Raffaele
Tetrahedron Letters, 2006 , vol. 47, # 6 p. 909 - 911
