5-溴-1,2-二甲基-1H-咪唑合成路线 (共 5 条)
反应条件
N-bromosuccinmide in dichloromethane T=0°C; 2 h;
参考文献
McLoughlin, Padraig T.F.; Clyne, Mairead A.; Aldabbagh, Fawaz
Tetrahedron, 2004 , vol. 60, # 37 p. 8065 - 8071
反应条件
potassium carbonate in N,N-dimethyl-formamide T=20°C;
参考文献
WO2009/819 A1, ;
Page/Page column 54 ;
WO 2009/000819 A1
反应条件
2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; sodium hydrogencarbonate; potassium bromide in dichloromethane T=0°C; 6 h;
参考文献
Organic Process Research and Development, , vol. 14, # 1 p. 142 - 151
参考文献
Bowman, W. Russell; Taylor, Peter F.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 4 p. 919 - 924
反应条件
ammonia; sodium in tert-butyl alcohol 0.0833333 h; Heatingother reagent and solvent; Mechanism;
参考文献
Symons, Martyn C.R.; Bowman, Russell; Taylor, Peter F.
Tetrahedron Letters, 1989 , vol. 30, # 11 p. 1409 - 1412