1,2-二甲基-1H-咪唑-5-甲醛合成路线 （共 4 条）
反应条件
1: With n-butyllithium in diethyl ether; hexane T=20°C; 1.5 h; 2: With N,N-dimethyl-formamide in diethyl ether; hexane 2 - 5 h;
参考文献
Schering Corporation
Patent: US2004/122018 A1, 2004 ;
Location in patent: Page 462-463 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide T=20°C; 6 h; Cooling with ice;
参考文献
Kyowa Hakko Kirin Co., Ltd.; Fukuda, Yuichi; Kanai, Toshimi; Nakasato, Yoshisuke; Kimpara, Keisuke
Patent: US2013/65905 A1, 2013 ;
Location in patent: Paragraph 0265 ;
反应条件
manganese(IV) oxide; methanesulfonic acid; tert-butyl alcohol T=20 - 85°C;
参考文献
Webel, Matthias; Palmer, Andreas Marc; Scheufler, Christian; Haag, Dieter; Mueller, Bernd
Organic Process Research and Development, 2010 , vol. 14, # 1 p. 142 - 151
反应条件
methanol; sodium tetrahydroborate T=0 - 20°C;
参考文献
PHARMASCIENCE, INC.; LAURENT, Alain; ROSE, Yannick; JAQUITH, James B.
Patent: WO2013/177668 A1, 2013 ;
Location in patent: Page/Page column 63-64 ;
