[2S-(2alpha,5alpha,6alpha)]-6-溴-3,3-二甲基-7-氧代-4-硫杂-1-氮杂双环[3.2.0]庚烷-2-羧酸合成路线 （共 2 条）
反应条件
1: dicyclocarbodiimide; 4-dimethylaminopyridine / CH2Cl2 / 25 °C 2: 45.3 g / aq. H2O2 / phenol / 25 °C 3: 90 percent / Zn; aq. NH4OAc / tetrahydrofuran / 6 - 8 °C 4: 94 percent / toluene / 2 h / Heating 5: I2 / CH2Cl2 / 25 °C 6: 7.24 g / aq. KMnO4 / acetic acid / 0.33 h / ultrasounds 7: 90 percent / m-cresol / 3 h / 50 °C View Scheme
参考文献
Xu, Wei Liang; Li, Yun Zheng; Zhang, Qing Shan; Zhu, He Sun
Synthesis, 2005 , # 3 art. no. F11904SS, p. 442 - 446
反应条件
89 h; Ambient temperaturepH 9.2 buffer; Yield given;
参考文献
Orlek; Sammes; Knott-Hunziker; Waley
Journal of the Chemical Society. Perkin transactions 1, 1980 , vol. 10, p. 2322 - 2329
