2-(1H-咪唑-1-基)-1-苯基-乙酮合成路线 （共 10 条）
参考文献
Popov, A. F.; Piskunova, Zh. P.; Matvienko, V. N.; Kondratenko, G. P.; Nikolenko, Yu. I.
Pharmaceutical Chemistry Journal, 1989 , vol. 23, # 10 p. 847 - 849
Khimiko-Farmatsevticheskii Zhurnal, 1989 , vol. 23, # 10 p. 1223 - 1226
反应条件
copper in xylene T=85°C; 13 h;
参考文献
Pellicciari; Curini; Spagnoli
Archiv der Pharmazie, 1984 , vol. 317, # 1 p. 38 - 41
反应条件
in N,N-dimethyl-formamide T=5 - 10°C; 3 h;
参考文献
Porretta, G. C.; Fioravanti, R.; Biava, M.; Cirilli, R.; Simonetti, N.; et al.
European Journal of Medicinal Chemistry, 1993 , vol. 28, # 10 p. 749 - 760
反应条件
tetrabutylammomium bromide; triethylamine in acetonitrile 10 h; Reflux;
参考文献
Rad, Mohammad Navid Soltani; Khalafi-Nezhad, Ali; Behrouz, Somayeh
Helvetica Chimica Acta, 2009 , vol. 92, # 9 p. 1760 - 1774
反应条件
1: 96 percent / acetone / 2 h / Ambient temperature 2: 56 percent / aq. NaOH / 1 h / Ambient temperature View Scheme
参考文献
Kamijo; Yamamoto; Harada; Iizuka
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 4 p. 1213 - 1221
反应条件
magnesium; acetic acid in methanol T=20°C;
参考文献
Tang, Guo; Ji, Tao; Hu, An-Fu; Zhao, Yu-Fen
Synlett, 2008 , # 12 p. 1907 - 1909
反应条件
sodium hydroxide; hydroxylamine hydrochloride in ethanol; water T=20°C; 24 h;
参考文献
Rad, Mohammad Navid Soltani; Khalafi-Nezhad, Ali; Behrouz, Somayeh
Helvetica Chimica Acta, 2009 , vol. 92, # 9 p. 1760 - 1774
反应条件
1: hydroxylamine 2: 76 percent / hydrogen / 10 percent palladium on charcoal / ethanol / 28 h / 20 °C / 51714.8 Torr View Scheme
参考文献
Fioravanti, Rossella; Biava, Mariangela; Porretta, Giulio Cesare; Artico, Marino; Lampis, Giorgio; Deidda, Delia; Pompei, Raffaello
Medicinal Chemistry Research, 1997 , vol. 7, # 2 p. 87 - 97
反应条件
sodium tetrahydroborate in ethanol 3 h; Heating;
参考文献
Porretta, G. C.; Fioravanti, R.; Biava, M.; Cirilli, R.; Simonetti, N.; et al.
European Journal of Medicinal Chemistry, 1993 , vol. 28, # 10 p. 749 - 760
反应条件
in N,N-dimethyl-formamide
2 h;
参考文献
Brown, Tom; Jones, John H.; Richards, John D.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , # 7 p. 1553 - 1562
