Nε-Boc-L-赖氨酸合成路线 （共 24 条）
反应条件
hydrogen; palladium on activated charcoal in methanol; water T=20°C; P=2327.2 - 2844.3 Torr;
参考文献
Scott, John W.; Parker, David; Parrish, David R.
Synthetic Communications, 1981 , vol. 11, # 4 p. 303 - 314
反应条件
sodium hydroxide in 1,4-dioxane; water T=20°C; pH=11; 12 h;
参考文献
Zheng, Yan; Duanmu, Chuansong; Gao, Yong
Organic Letters, 2006 , vol. 8, # 15 p. 3215 - 3217
反应条件
tri-n-butyl-tin hydride; bis-triphenylphosphine-palladium(II) chloride in dichloromethane Ambient temperature;
参考文献
Guibe, F.; Dangles, O.; Balavoine, G.
Tetrahedron Letters, 1986 , vol. 27, # 21 p. 2365 - 2368
反应条件
1: 866 g / tetramethylguanidine / dimethylsulfoxide / 4.5 h / 50 °C 2: 98 percent / H2 / Pd/C / methanol; H2O / 20 °C / 2327.2 - 2844.3 Torr View Scheme
参考文献
Synthetic Communications, , vol. 11, # 4 p. 303 - 314
反应条件
1: aq. MgO 2: H2 / Pd / acetic acid View Scheme
参考文献
Journal of the American Chemical Society, , vol. 87, p. 99 - 104
反应条件
sodium hydroxide; 4-(N,N-dimethlyamino)pyridine in tetrahydrofuran; water T=0°C; pH=12; Product distribution / selectivity;
参考文献
WO2008/14811 A1, ;
Page/Page column 13-14 ;
反应条件
dimethyl sulfoxide T=120°C; 0.25 h; Microwave irradiation;
参考文献
Hoeck, Stefan; Marti, Roger; Riedl, Rainer; Simeunovic, Marina
Chimia, 2010 , vol. 64, # 3 p. 200 - 202
反应条件
1: 866 g / tetramethylguanidine / dimethylsulfoxide / 4.5 h / 50 °C 2: 98 percent / H2 / Pd/C / methanol; H2O / 20 °C / 2327.2 - 2844.3 Torr View Scheme
参考文献
Synthetic Communications, , vol. 11, # 4 p. 303 - 314
反应条件
1: 1.) NaOH, 2.) aq. HCl / 1) -20 - -5.5 deg C, H2O, EtOH; 2) 50 deg C 2: 866 g / tetramethylguanidine / dimethylsulfoxide / 4.5 h / 50 °C 3: 98 percent / H2 / Pd/C / methanol; H2O / 20 °C / 2327.2 - 2844.3 Torr View Scheme
参考文献
Synthetic Communications, , vol. 11, # 4 p. 303 - 314
反应条件
1: 81 percent / aq. LiOH / 3 - 5 °C 2: 1.) NaOH, 2.) aq. HCl / 1) -20 - -5.5 deg C, H2O, EtOH; 2) 50 deg C 3: 866 g / tetramethylguanidine / dimethylsulfoxide / 4.5 h / 50 °C 4: 98 percent / H2 / Pd/C / methanol; H2O / 20 °C / 2327.2 - 2844.3 Torr View Scheme
参考文献
Synthetic Communications, , vol. 11, # 4 p. 303 - 314
