2,3-吡啶二羧酸-3-甲酯合成路线 （共 11 条）
反应条件
in methanol 1 h; Heating / reflux;
参考文献
WO2006/106326 A1, ;
Page/Page column 129 ;
WO 2006/106326 A1
参考文献
Monatshefte fuer Chemie, , vol. 27, p. 364
Monatshefte fuer Chemie, , vol. 28, p. 441
Journal of the Chemical Society, , p. 2531,2534
Journal of the American Chemical Society, , vol. 64, p. 1721
反应条件
1: acetic anhydride / 4 h / Heating 2: 24 h / 45 °C View Scheme
参考文献
Chemistry of Heterocyclic Compounds, , vol. 38, # 3 p. 306 - 309
反应条件
in methanol Hydrolysis;
参考文献
Journal of Heterocyclic Chemistry, , vol. 36, # 4 p. 979 - 984
参考文献
Heterocyclic Communications, , vol. 7, # 5 p. 439 - 444
Chemistry of Heterocyclic Compounds, , vol. 38, # 3 p. 306 - 309
参考文献
Kenyon; Thaker
Journal of the Chemical Society, 1957 , p. 2531,2534
参考文献
Kenyon; Thaker
Journal of the Chemical Society, 1957 , p. 2531,2534
参考文献
Kirpal
Monatshefte fuer Chemie, 1906 , vol. 27, p. 364
Monatshefte fuer Chemie, 1907 , vol. 28, p. 441
反应条件
thionyl chloride
1).reflux, 4 hrs., 2).-15 deg C, 40 min., than temp. was raised to r.t. during 20 min.; Yield given. Multistep reaction;
参考文献
Chapyshev, S.V.; Kartsev, V.G.; Sipyagin, A.M.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1983 , vol. 19, p. 882 - 886
Khimiya Geterotsiklicheskikh Soedinenii, 1983 , vol. 19, # 8 p. 1098 - 1102
反应条件
diphenyl phosphoryl azide; triethylamine
T=20°C; 4.08333 h; Heating / reflux;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2006/106326 A1, 2006 ;
Location in patent: Page/Page column 129 ;
WO 2006/106326 A1
