N-[(3S)-四氢-2,6-二氧代-2H-吡喃-3-基]-氨基甲酸叔丁酯合成路线 （共 3 条）
反应条件
acetic anhydride T=55°C; 0.25 h;
参考文献
Crepin, Alain; Wattier, Nicolas; Petit, Sylvain; Bischoff, Laurent; Fruit, Corinne; Marsais, Francis
Organic and Biomolecular Chemistry, 2009 , vol. 7, # 1 p. 128 - 134
反应条件
dicyclohexyl-carbodiimide in ethyl acetate Cyclization; 0.5 h;
参考文献
Krys'ko; Kabanov; Kabanova; Belikova; Mazepa
Pharmaceutical Chemistry Journal, 1998 , vol. 32, # 6 p. 304 - 306
反应条件
1: 60 percent / tetrahydrofuran / Ambient temperature
2: 95 percent / HCl (gas) / diethyl ether / 1 h
3: 75 percent / LiAlH4 / tetrahydrofuran / Heating
4: 56 percent / phenol / 19 h / 125 °C
View Scheme
参考文献
Witiak, Donald T.; Grattan, David A.; Heaslip, Richard J.; Rahwan, Ralf G.
Journal of Medicinal Chemistry, 1981 , vol. 24, # 6 p. 712 - 717
