N-(2-羟基乙基)水杨酰胺合成路线 （共 14 条）
反应条件
sodium hydroxide in water; acetonitrile T=30°C; pH=11.34-11.84; Rate constant;
参考文献
Khan, Mohammad Niyaz
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1989 , p. 199 - 208
参考文献
Phillips; Baltzly
Journal of the American Chemical Society, 1947 , vol. 69, p. 200,203
反应条件
thionyl chloride in chloroform T=0°C; 3 h;
参考文献
Peterson et al.
Journal of the American Chemical Society, 1980 , vol. 102, p. 7715
反应条件
1: 1.) p-toluenesulfonic acid, 2.) 3N aq. HCl / 1.) toluene, 2 h, reflux, 2.) THF, 24 h, reflux 2: 95 percent / thionyl chloride / CHCl3 / 3 h / Heating 3: 88 percent / silver nitrate / acetonitrile / 2 h / Heating View Scheme
参考文献
Benedini, Francesca; Bertolini, Giorgio; Cereda, Roberta; Dona, Giancarlo; Gromo, Gianni; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 1 p. 130 - 136
