2-(4-溴甲基苯基)苯并噻唑合成路线 (共 7 条)
反应条件
N-bromosuccinmide in tetrachloromethane 4 h; Reflux;
参考文献
Shi, He-Ping; Shi, Li-Wen; Dai, Jian-Xin; Xu, Lei; Wang, Mei-Hua; Wu, Xiao-Huan; Fang, Li; Dong, Chuan; Choi, Martin M. F.
Tetrahedron, 2012 , vol. 68, # 47 p. 9788 - 9794,7
反应条件
1: 21 percent 2: 51 percent / N-bromosuccinimide View Scheme
参考文献
Lin, Tzu-Chau; He, Guang S.; Prasad, Paras N.; Tan, Loon-Seng
Journal of Materials Chemistry, 2004 , vol. 14, # 6 p. 982 - 991
反应条件
1: polyphosphoric acid 2: NBS, (PhCO)2O2 / CCl4 / Heating; Irradiation View Scheme
参考文献
Palmer; Hall; Trigg; Warrington
Journal of medicinal chemistry, 1971 , vol. 14, # 12 p. 1223 - 1225
反应条件
1: 1-methyl-pyrrolidin-2-one / Heating 2: NBS; BPO / CCl4 / Heating View Scheme
参考文献
Mouysset; De Saqui-Sannes; Younes; Bellan; Payard; Tisne-Versailles
Farmaco, 1990 , vol. 45, # 9 p. 945 - 952
反应条件
1: 83 percent / Et3N / diethyl ether / 12 h 2: 80 percent / tetrahydrofuran / 0.25 h / 20 °C 3: 75 percent / N-bromosuccinimide; peroxyde de benzoyle / CCl4 / 3 h / Heating View Scheme
参考文献
Harizi, Abdallah; Zantour, Hedi
Phosphorus, Sulfur and Silicon and the Related Elements, 2004 , vol. 179, # 9 p. 1883 - 1891
反应条件
1: 1-methyl-pyrrolidin-2-one / 72 h / 110 °C 2: N-bromosuccinmide / tetrachloromethane / 1 h / Reflux; Irradiation View Scheme
参考文献
Wang, Guan; Zhang, Xinhai; Geng, Junlong; Li, Kai; Ding, Dan; Pu, Kan-Yi; Cai, Liping; Lai, Yee-Hing; Liu, Bin
Chemistry - A European Journal, 2012 , vol. 18, # 31 p. 9705 - 9713
反应条件
T=130 - 140°C; 0.25 h;
参考文献
Yoshino; Goto; Kohno; Morita; Tsukamoto
Chemical and pharmaceutical bulletin, 1990 , vol. 38, # 3 p. 676 - 680