(R)-1-BOC-2-氰基哌啶合成路线 （共 2 条）
反应条件
triethylamine; trifluoroacetic anhydride in tetrahydrofuran T=0 - 20°C; 18 h; Inert atmosphere;
参考文献
Barker, Graeme; Alshawish, Madeha R.; Skilbeck, Melanie C.; Coldham, Iain
Angewandte Chemie - International Edition, 2013 , vol. 52, # 30 p. 7700 - 7703
Angew. Chem., 2013 , vol. 125, # 30 p. 7854 - 7857,4
反应条件
1.1: chloroformic acid ethyl ester; triethylamine / tetrahydrofuran / 1 h / -15 °C / |Inert atmosphere 1.2: 16 h / |Inert atmosphere 2.1: triethylamine; trifluoroacetic anhydride / tetrahydrofuran / 18 h / 0 - 20 °C / |Inert atmosphere View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 30 p. 7700 - 7703
Angew. Chem., , vol. 125, # 30 p. 7854 - 7857,4
