4-(苄氧基)-5-甲氧基-2-硝基苯甲醛合成路线 （共 24 条）
反应条件
1.1: potassium permanganate / acetone / 2 h / 30 - 50 °C
2.1: oxalyl dichloride / toluene / 2 h / Reflux
2.2: 2 h
3.1: acetic acid / 0.17 h / 90 °C
3.2: 1 h / Reflux
View Scheme
参考文献
HANMI HOLDINGS CO., LTD.; BAE, In Hwan; BYUN, Eun Young; JU, Hae Kyoung; SONG, Ji Young; JUNG, Seung Hyun; JUN, Mi Ae; KIM, Ho Seok; JUNG, Young Hee; SHIM, Mi Yon; AHN, Young Gil; KIM, Maeng Sup
Patent: WO2012/30160 A2, 2012 ;
反应条件
sodium tetrahydroborate in methanol
参考文献
Scalzo; Artico; Giuliano; et al.
Farmaco, Edizione Scientifica, 1977 , vol. 32, # 8 p. 579 - 591
反应条件
1: permanganate de potassium
2: 100 percent
View Scheme
参考文献
Scalzo; Artico; Giuliano; et al.
Farmaco, Edizione Scientifica, 1977 , vol. 32, # 8 p. 579 - 591
反应条件
1: FeSO4*7H2O, 25 percent NH4OH / 0.08 h / 100 °C
2: 20 percent HBr; NaNO2; 47 percent HBr / CuBr
View Scheme
参考文献
Kobayashi, Shigeru; Okimoto, Kazuto; Imakura, Yasuhiro
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 5 p. 1567 - 1573
