4-苄氧基-3-甲氧基苯甲醛合成路线 （共 139 条）
反应条件
potassium hydroxide in ethanol; water
2 h;
参考文献
Ahvonen, Toivo; Brunow, Goesta; Kristersson, Per; Lundquist, Knut
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1983 , vol. 37, # 9 p. 845 - 850
反应条件
1: Ag2O
2: HNO2
3: 62 percent / H2 / 10percent Pd/C
4: 83 percent
View Scheme
参考文献
Mori, Miwako; Ishikura, Minoru; Ikeda, Toshihito; Ban, Yoshio
Heterocycles, 1984 , vol. 22, # 2 p. 253 - 256
反应条件
1.1: 77.2 percent / NaH / tetrahydrofuran / 0.17 h / 80 °C / microwave conditions
2.1: I2; NaBH4 / tetrahydrofuran
2.2: aq. H2O2; NaOH
3.1: 85 percent / I2; imidazole; PPh3 / CH2Cl2
4.1: 100 percent / toluene
5.1: 71 percent / n-BuLi / tetrahydrofuran
6.1: 73 percent / H2 / Pd/C
View Scheme
参考文献
Su, Chung-Ren; Shen, Yuh-Chiang; Kuo, Ping-Chung; Leu, Yann-Lii; Damu, Amooru G.; Wang, Yea-Hwey; Wu, Tian-Shung
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 24 p. 6155 - 6160
反应条件
n-butyllithium
1.) THF, RT, 15 min, 2.) 30 min; Yield given. Multistep reaction;
参考文献
Giles, Robin G. F.; Son, Vanessa R. Lee; Sargent, Melvyn V.
Australian Journal of Chemistry, 1990 , vol. 43, # 4 p. 777 - 781
反应条件
1.1: sodium methoxide / methanol / 5.5 h / Heating
1.2: 78 percent / aq. HCl / H2O / 0 °C
2.1: 90 percent / Mg / methanol / 5.5 h / 0 °C
3.1: LiBH4 / tetrahydrofuran / 5.5 h / Heating
3.2: 48 percent / aq. HCl / tetrahydrofuran / 15 h / 20 °C
View Scheme
参考文献
Loriot; Thomas; Brown
Bulletin de la Societe Chimique de France, 1985 , vol. NO. 5, p. 871 - 875
反应条件
1: (i) K, tBuOH, (heating), (ii) /BRN= 385737/, NaOAc
2: aq. KOH / ethanol / Heating
View Scheme
参考文献
Cooke,R.G.; Owen,W.R.
Australian Journal of Chemistry, 1962 , vol. 15, p. 486 - 491
反应条件
1: diethyl ether; tetrahydrofuran / 1 h / 20 °C
2: NaO-tBu; cyclohexanone / toluene / 0.5 h / Heating
View Scheme
参考文献
Tilley, Jefferson W.; Clader, John W.; Wirkus, Maria; Blount, John F.
Journal of Organic Chemistry, 1985 , vol. 50, # 13 p. 2220 - 2224
反应条件
1: 71 percent / KOH, tetrabutylammonium bromide / ethanol / 1 h / 0 °C
2: 93 percent / ammonium formate / 5percent Pd/C / ethanol / 2 h / 18 - 20 °C
View Scheme
参考文献
Axelrod et al.
Journal of Biological Chemistry, 1958 , vol. 233, p. 697
反应条件
1: LDA / tetrahydrofuran / -94 °C
2: H2 / Pd/C / ethyl acetate
View Scheme
参考文献
Plourde, Guy L.
Tetrahedron Letters, 2002 , vol. 43, # 19 p. 3597 - 3599
反应条件
hydrogenchloride in chloroform
Ambient temperature;
参考文献
Sheldrake, Peter W.; Suckling, Keith E.; Woodhouse, Robert N.; Murtagh, Amanda J.; Herbert, Richard B.; Barker, Alan C.; Staunton, James; Battersby, Alan R.
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 18 p. 3003 - 3009
