4-苄氧基-3-甲氧基苯甲醛合成路线 （共 139 条）
反应条件
1: Ag2O 2: HNO2 View Scheme
参考文献
HANMI HOLDINGS CO., LTD.; BAE, In Hwan; BYUN, Eun Young; JU, Hae Kyoung; SONG, Ji Young; JUNG, Seung Hyun; JUN, Mi Ae; KIM, Ho Seok; JUNG, Young Hee; SHIM, Mi Yon; AHN, Young Gil; KIM, Maeng Sup
Patent: WO2012/30160 A2, 2012 ;
反应条件
1: With piperidine; pyridine T=90°C; Reflux; 2: With water 1 h; Cooling with ice;
参考文献
Ley, Jakob P.; Paetz, Susanne; Blings, Maria; Hoffmann-Luecke, Petra; Bertram, Heinz-Juergen; Krammer, Gerhard E.
Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 15 p. 6656 - 6664
反应条件
1: Methyltriphenylphosphonium bromide With potassium tert-butylate in tetrahydrofuran T=0 - 20°C; Inert atmosphere; 2: 4-benzyloxy-3-methoxy-benzaldehyde in tetrahydrofuran 2 h;
参考文献
Koolaji, Nooshin; Abu-Mellal, Abdallah; Tran, Van H.; Duke, Rujee K.; Duke, Colin C.
European Journal of Medicinal Chemistry, 2013 , vol. 63, p. 415 - 422
反应条件
sodium hydride in tetrahydrofuran T=80°C; Wittig reaction; 0.166667 h; microwave conditions;
参考文献
Su, Chung-Ren; Shen, Yuh-Chiang; Kuo, Ping-Chung; Leu, Yann-Lii; Damu, Amooru G.; Wang, Yea-Hwey; Wu, Tian-Shung
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 24 p. 6155 - 6160
反应条件
1: 73 percent / ammonium acetate / 1.5 h / Heating 2: 55 percent / lithium aluminum hydride / diethyl ether; tetrahydrofuran / 1.) reflux, 2 h, 2.) room temperature, overnight 3: formic acid / 48 h / 50 °C 4: 88 percent / ammonium sulfate / toluene / 48 h / Heating 5: t-BuLi / 1.) THF, hexane, -78 deg C, 30 min, 2.) -100 deg C, 4 h 6: hydrazine, acetic acid / ethanol; H2O / 2 h / Ambient temperature 7: K2CO3 / acetone / 14 h / Heating 8: lithium aluminum hydride / tetrahydrofuran / Heating 9: 0.026 g / hydrogen / 10percent Pd/C / acetic acid; methanol / 6 h / 2585.7 Torr View Scheme
参考文献
Meyers, A. I.; Guiles, Joseph
Heterocycles, 1989 , vol. 28, # 1 p. 295 - 301
反应条件
1: potassium permanganate; acetone 2: diethyl ether; thionyl chloride; pyridine View Scheme
参考文献
Lovecy; Robinson; Sugasawa
Journal of the Chemical Society, 1930 , p. 817,818
反应条件
1: ethanolic NH3; Raney nickel / 50 - 60 °C / 44130.5 Torr / Hydrogenation 2: pyridine 3: palladium/charcoal; ethanol / Hydrogenation View Scheme
参考文献
Buzas; Dufour
Annales Pharmaceutiques Francaises, 1959 , vol. 17, p. 453
参考文献
DE549432 , ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 17, p. 575
反应条件
1: NaBH4 / methanol 2: PBr3 / diethyl ether 3: (i) nBuLi, THF, (ii) /BRN= 2130929/, (iii) aq. NaIO4, MeOH 4: H2 / Pd-C / methanol View Scheme
参考文献
Chemische Berichte, , vol. 112, # 11 p. 3703 - 3714
反应条件
1: peroxoformic acid / Ambient temperature 2: standard procedure 3: hydrogen / Pd/C View Scheme
参考文献
Magnetic Resonance in Chemistry, , vol. 28, # 11 p. 973 - 978
