11H-10,11-二氮杂苯并[b]芴合成路线 （共 72 条）
反应条件
1: 97 percent / POCl3 / 3 h / Heating
2: 92 percent / Raney nickel / dioxane / 3 h / Heating
View Scheme
参考文献
Bergman, Jan; Engqvist, Robert; Stalhandske, Claes; Wallberg, Hans
Tetrahedron, 2003 , vol. 59, # 7 p. 1033 - 1048
反应条件
1: 65 percent / diphenyl ether / 3.5 h / Heating
2: 97 percent / POCl3 / 3 h / Heating
3: 92 percent / Raney nickel / dioxane / 3 h / Heating
View Scheme
参考文献
Bergman, Jan; Engqvist, Robert; Stalhandske, Claes; Wallberg, Hans
Tetrahedron, 2003 , vol. 59, # 7 p. 1033 - 1048
反应条件
1: 94 percent / aq. HCl / 30 h / Heating
2: 92 percent / Raney nickel / dioxane / 3 h / Heating
View Scheme
参考文献
Bergman, Jan; Engqvist, Robert; Stalhandske, Claes; Wallberg, Hans
Tetrahedron, 2003 , vol. 59, # 7 p. 1033 - 1048
反应条件
1: 85 percent / CuI, NaH / bis-(2-methoxy-ethyl) ether / 1.) r.t., 30 min, 2.) r.t., 30 h
2: 90 percent / TBAF / tetrahydrofuran / 6 h / Heating
View Scheme
参考文献
Molina; Fresneda; Delgado
Synthesis, 1999 , # 2 p. 326 - 329
反应条件
1: toluene / 0 - 20 °C
2: toluene / 14 h / Heating
3: 85 percent / CuI, NaH / bis-(2-methoxy-ethyl) ether / 1.) r.t., 30 min, 2.) r.t., 30 h
4: 90 percent / TBAF / tetrahydrofuran / 6 h / Heating
View Scheme
参考文献
Molina; Fresneda; Delgado
Synthesis, 1999 , # 2 p. 326 - 329
反应条件
1: 86 percent / dicyclohexylcarbodiimide; 4-(dimethylamino)pyridine / tetrahydrofuran / 3 h / Heating
2: 98 percent / Br2 / CHCl3 / 1.5 h / Heating
3: 57 percent / NaOMe / CHCl3
4: 32 percent / Na2S2O6*2H2O / methanol; H2O / 18 h / Heating
5: 72 percent / Fe / acetic acid; ethanol / 1 h / Heating
View Scheme
参考文献
Ho, Tse-Lok; Jou, Der-Guey
Helvetica Chimica Acta, 2002 , vol. 85, # 11 p. 3823 - 3827
反应条件
1: 98 percent / Br2 / CHCl3 / 1.5 h / Heating
2: 57 percent / NaOMe / CHCl3
3: 32 percent / Na2S2O6*2H2O / methanol; H2O / 18 h / Heating
4: 72 percent / Fe / acetic acid; ethanol / 1 h / Heating
View Scheme
参考文献
Ho, Tse-Lok; Jou, Der-Guey
Helvetica Chimica Acta, 2002 , vol. 85, # 11 p. 3823 - 3827
反应条件
1: 32 percent / Na2S2O6*2H2O / methanol; H2O / 18 h / Heating
2: 72 percent / Fe / acetic acid; ethanol / 1 h / Heating
View Scheme
参考文献
Ho, Tse-Lok; Jou, Der-Guey
Helvetica Chimica Acta, 2002 , vol. 85, # 11 p. 3823 - 3827
反应条件
1: 57 percent / NaOMe / CHCl3
2: 32 percent / Na2S2O6*2H2O / methanol; H2O / 18 h / Heating
3: 72 percent / Fe / acetic acid; ethanol / 1 h / Heating
View Scheme
参考文献
Ho, Tse-Lok; Jou, Der-Guey
Helvetica Chimica Acta, 2002 , vol. 85, # 11 p. 3823 - 3827
反应条件
1.1: iodine; caesium carbonate / acetonitrile / 9 h / 23 - 25 °C
1.2: 6 h / 23 - 25 °C
2.1: AlCl3, aluminium chloride / benzene / 9 h / Reflux
View Scheme
参考文献
Ali, Shaukat; Li, Ying-Xiu; Anwar, Saeed; Yang, Fang; Chen, Zi-Sheng; Liang, Yong-Min
Journal of Organic Chemistry, 2012 , vol. 77, # 1 p. 424 - 431
