1: 16 percent / aq. NaOH / ethanol / 1 h / Heating 2: 77 percent / NEt3 / ethanol / Ambient temperature 3: 79 percent / sat. NaHCO3 / methanol / 0.08 h / Heating 4: 89 percent / PCl3 / CHCl3 / 1 h / Heating View Scheme

1: 77 percent / NEt3 / ethanol / Ambient temperature 2: 79 percent / sat. NaHCO3 / methanol / 0.08 h / Heating 3: 89 percent / PCl3 / CHCl3 / 1 h / Heating View Scheme

1: 79 percent / sat. NaHCO3 / methanol / 0.08 h / Heating 2: 89 percent / PCl3 / CHCl3 / 1 h / Heating View Scheme

1: 1,4-dioxane; N,N-dimethyl-formamide / 0 - 20 °C 2: N,N-dimethyl-formamide / 18 h 3: polyphosphoric acid / 2 h / 130 °C 4: trichlorophosphate / 2 h / 130 °C 5: palladium 10 on activated carbon; hydrogen; sodium acetate; acetic acid / 2 h / 3102.97 Torr View Scheme

1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0.17 h / 0 °C / Inert atmosphere 1.2: 0.5 h / Inert atmosphere 2.1: tris-(dibenzylideneacetone)dipalladium(0); caesium carbonate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene / toluene / 0.08 h / 20 °C / Inert atmosphere 2.2: 16 h / 110 °C / Inert atmosphere 3.1: potassium tert-butylate / dimethyl sulfoxide / 0.17 h / 20 °C / Inert atmosphere View Scheme

1.1: tris-(dibenzylideneacetone)dipalladium(0); caesium carbonate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene / toluene / 0.08 h / 20 °C / Inert atmosphere 1.2: 16 h / 110 °C / Inert atmosphere 2.1: potassium tert-butylate / dimethyl sulfoxide / 0.17 h / 20 °C / Inert atmosphere View Scheme

1.1: palladium 10 on activated carbon; sodium carbonate; triphenylphosphine / ethylene glycol dimethyl ether / 16 h / 80 °C / Inert atmosphere 2.1: palladium 10 on activated carbon; hydrogen / tetrahydrofuran / 16 h / 20 °C / Inert atmosphere 3.1: toluene-4-sulfonic acid / acetonitrile / 10 - 15 °C / Inert atmosphere 3.2: 1.17 h / 20 °C / Inert atmosphere 4.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0.17 h / 0 °C / Inert atmosphere 4.2: 0.5 h / Inert atmosphere 5.1: tris-(dibenzylideneacetone)dipalladium(0); caesium carbonate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene / toluene / 0.08 h / 20 °C / Inert atmosphere 5.2: 16 h / 110 °C / Inert atmosphere 6.1: potassium tert-butylate / dimethyl sulfoxide / 0.17 h / 20 °C / Inert atmosphere View Scheme

1.1: palladium 10 on activated carbon; hydrogen / tetrahydrofuran / 16 h / 20 °C / Inert atmosphere 2.1: toluene-4-sulfonic acid / acetonitrile / 10 - 15 °C / Inert atmosphere 2.2: 1.17 h / 20 °C / Inert atmosphere 3.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0.17 h / 0 °C / Inert atmosphere 3.2: 0.5 h / Inert atmosphere 4.1: tris-(dibenzylideneacetone)dipalladium(0); caesium carbonate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene / toluene / 0.08 h / 20 °C / Inert atmosphere 4.2: 16 h / 110 °C / Inert atmosphere 5.1: potassium tert-butylate / dimethyl sulfoxide / 0.17 h / 20 °C / Inert atmosphere View Scheme

1.1: palladium 10 on activated carbon; sodium carbonate; triphenylphosphine / ethylene glycol dimethyl ether / 16 h / 80 °C / Inert atmosphere 2.1: palladium 10 on activated carbon; hydrogen / tetrahydrofuran / 16 h / 20 °C / Inert atmosphere 3.1: toluene-4-sulfonic acid / acetonitrile / 10 - 15 °C / Inert atmosphere 3.2: 1.17 h / 20 °C / Inert atmosphere 4.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0.17 h / 0 °C / Inert atmosphere 4.2: 0.5 h / Inert atmosphere 5.1: tris-(dibenzylideneacetone)dipalladium(0); caesium carbonate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene / toluene / 0.08 h / 20 °C / Inert atmosphere 5.2: 16 h / 110 °C / Inert atmosphere 6.1: potassium tert-butylate / dimethyl sulfoxide / 0.17 h / 20 °C / Inert atmosphere View Scheme

1.1: n-butyllithium / hexane; tetrahydrofuran / 0.5 h / -70 °C / |Inert atmosphere 2.1: sec.-butyllithium / tetrahydrofuran; pentane / 1 h / -70 °C / |Inert atmosphere 2.2: 1 h / -70 °C / |Inert atmosphere 2.3: |Inert atmosphere 3.1: hydrogen; palladium 10 on activated carbon / methanol; chloroform / 12 h / 1810.07 Torr View Scheme