反应条件
1: 85 percent / trifluoroacetic anhydride (TFAA) / CH2Cl2 / 576 h / Ambient temperature 2: 100 percent / Raney nickel (W-2) / acetone / 1 h / Heating 3: 1.04 g / K2CO3 / methanol; CH2Cl2 / 0.5 h / Ambient temperature 4: 1.) dimethyl sulfoxide, oxalyl chloride, 2.) triethylamine / 1.) dichloromethane, -60 deg C, 40 min, 2.) dichloromethane, from -60 deg C to RT, 60 min 5: 78 percent / KOH, iodobenzene diacetate / methanol / 3 h / 0 °C 6: 83 mg / 70 percent sodium bis(2-methoxyethoxy)aluminum hydride in toluene / benzene / Heating 7: 85 percent / p-toluenesulfonic acid (PTSA) monohydrate / tetrahydrofuran / 1.5 h / Heating View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 41, # 2 p. 276 - 281
