2,6-二溴-4-甲基苯酚合成路线 （共 81 条）
参考文献
Journal of the Chemical Society, , p. 525
参考文献
Journal of the Chemical Society, , p. 525
反应条件
pyridine; sodium methylate; sodium; Copper(I)chloride in methanol; toluene
参考文献
Hoffmann-La Roche Inc.
Patent: US4218567 A1, 1980 ;
反应条件
copper(I) bromide in water; N,N-dimethyl-formamide
参考文献
Bovicelli, Paolo; Antonioletti, Roberto; Barontini, Maurizio; Borioni, Giorgio; Bernini, Roberta; Mincione, Enrico
Tetrahedron Letters, 2005 , vol. 46, # 8 p. 1255 - 1257
反应条件
1: potassium hydroxide / 1,4-dioxane / 0.6 h / 65 °C 2: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / 37 h / |Inert atmosphere; |Reflux 3: potassium carbonate / methanol / 20 °C 4: acetic acid; palladium 10 on activated carbon; sodium tetrahydroborate / isopropyl alcohol / 1.5 h / 20 °C 5: boron tribromide / dichloromethane / 18.5 h / 0 - 20 °C View Scheme
参考文献
Zhao, Wenjun; Huang, Li; Guan, Yong; Wulff, William D.
Angewandte Chemie - International Edition, 2014 , vol. 53, # 13 p. 3436 - 3441
Angew. Chem., 2014 , vol. 126, # 13 p. 3504 - 3509,6
反应条件
1: concentrated alcohol 2: hydrochloride of tin dichloride; glacial acetic acid View Scheme
参考文献
Thiele; Eichwede
Justus Liebigs Annalen der Chemie, 1900 , vol. 311, p. 366 Anm.
反应条件
in diethyl ether T=37°C; 24 h;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2617 - 2625
反应条件
in diethyl ether T=37°C; 24 h;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2617 - 2625
参考文献
Autenrieth; Beuttel
Archiv der Pharmazie (Weinheim, Germany), 1910 , vol. 248, p. 123
反应条件
oxygen; [Co(O2CCH3)2]*4H2O; sodium hydroxide in ethylene glycol T=80°C; P=760.051 Torr; 8 h; Reagent/catalystTemperature;
参考文献
Jiang, Jian-An; Chen, Cheng; Guo, Ying; Liao, Dao-Hua; Pan, Xian-Dao; Ji, Ya-Fei
Green Chemistry, 2014 , vol. 16, # 5 p. 2807 - 2814
