4,5-二溴-2-呋喃甲醛合成路线 （共 10 条）
反应条件
1: With aluminum tri-bromide in 1,1-dibromomethane T=5 - 15°C; 1.5 h; 2: With bromine in 1,1-dibromomethane T=20°C; 19 h; 3: With water in 1,1-dibromomethane
参考文献
Wyeth
Patent: US2006/35930 A1, 2006 ;
Location in patent: Page/Page column 11 ;
US 20060035930 A1
反应条件
N-bromosuccinmide in tetrachloromethane T=-5°C; 22 h;
参考文献
Asian Journal of Chemistry, , vol. 24, # 2 p. 927 - 928
反应条件
n-butyllithium; diisopropylamine in tetrahydrofuran T=-80°C; 0.166667 h;
参考文献
Bulletin des Societes Chimiques Belges, , vol. 105, # 10-11 p. 615 - 634
反应条件
AlCl3, aluminium chloride; bromine in 1,2-dichloro-ethane T=0°C; 16 h;
参考文献
Asian Journal of Chemistry, , vol. 24, # 2 p. 927 - 928
反应条件
ammonium nitrate in ethanol 4 h; Heating;
参考文献
Chiarello; Joullie
Tetrahedron, 1988 , vol. 44, # 1 p. 41 - 48
反应条件
1: 84 percent / ammonium nitrate / ethanol / 4 h / Heating 2: 89 percent / n-BuLi / diethyl ether / -78 deg C up to 0 deg C within 2 h View Scheme
参考文献
Chiarello; Joullie
Tetrahedron, 1988 , vol. 44, # 1 p. 41 - 48
反应条件
in diethyl ether 1 h; Irradiationphotochemical debromination was investigated; Product distribution;
参考文献
Antonioletti, Roberto; D'Auria, Maurizio; Mico, Antonella De; Piancatelli, Giovanni; Scettri, Arrigo
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1285 - 1288
反应条件
water; silver nitrate T=20°C; 4 h;
参考文献
Zheng, Fei Lang; Ban, Shu Rong; Feng, Xiu E; Zhao, Cheng Xiao; Lin, Wenhan; Li, Qing Shan
Molecules, 2011 , vol. 16, # 6 p. 4897 - 4911
反应条件
1: water; silver nitrate / 4 h / 20 °C 2: thionyl chloride; N,N-dimethyl-formamide / 5 h / 80 - 90 °C View Scheme
参考文献
Zheng, Fei Lang; Ban, Shu Rong; Feng, Xiu E; Zhao, Cheng Xiao; Lin, Wenhan; Li, Qing Shan
Molecules, 2011 , vol. 16, # 6 p. 4897 - 4911
反应条件
1: 61 percent / CuI, Et2NH / PdCl2(PPh3)2 / 24 h / Ambient temperature
2: tetrahydrofuran / 3 h / Heating
3: PdCl2(PPh3)2 / tetrahydrofuran / 16 h / Heating
4: 84 percent / hydrogen / Pd(OH)2/C / ethyl acetate / 1 h / Ambient temperature
View Scheme
参考文献
Bach, Thorsten; Krueger, Lars
Tetrahedron Letters, 1998 , vol. 39, # 13 p. 1729 - 1732
