2-(7-甲氧基-1H-吲哚-3-基)乙基氯化铵合成路线 （共 8 条）
反应条件
hydrogen; palladium on activated charcoal in ethanol P=2585.7 Torr; 12 h;
参考文献
Repke, David B.; Grotjahn, Douglas B.; Shulgin, Alexander T.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 7 p. 892 - 896
反应条件
hydrogenchloride; hydrazine hydrate in methanol; ethanol; chloroform
参考文献
Eli Lilly and Company
Patent: US5635528 A1, 1997 ;
US 5635528 A
反应条件
1: TFA / 20 °C 2: LAH / tetrahydrofuran View Scheme
参考文献
Yamada, Fumio; Saida, Yoshihiro; Somei, Masanori
Heterocycles, 1986 , vol. 24, # 9 p. 2619 - 2627
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 1 h; Heating;
参考文献
Yamada, Fumio; Saida, Yoshihiro; Somei, Masanori
Heterocycles, 1986 , vol. 24, # 9 p. 2619 - 2627
反应条件
1: 50 percent / hydrazine hydrate / Raney nickel / methanol; tetrahydrofuran / 1 h / 60 °C 2: 50 percent / tert-butylcatechol / xylene / 3 h / Heating 3: 95 percent / H2 / 10 percent Pd/C / ethanol / 12 h / 2585.7 Torr View Scheme
参考文献
Repke, David B.; Grotjahn, Douglas B.; Shulgin, Alexander T.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 7 p. 892 - 896
反应条件
1: 96 percent / KOH / ethanol; H2O / 5.5 h / Heating 2: 72 percent / conc. H2SO4 / H2O / 5 h View Scheme
参考文献
Soti; Incze; Kardos-Balogh; Kajtar-Peredy; Szantay
Synthetic Communications, 1993 , vol. 23, # 12 p. 1689 - 1698
反应条件
1: 93.7 percent / NH4OAc / 2.5 h / 103 - 107 °C 2: 88.2 percent / LiAlH4 / tetrahydrofuran / 1 h / Heating View Scheme
参考文献
Nelson, Hosea M.; Reisberg, Solomon H.; Shunatona, Hunter P.; Patel, Jigar S.; Toste, F. Dean
Angewandte Chemie - International Edition, 2014 , vol. 53, # 22 p. 5600 - 5603
Angew. Chem., 2014 , vol. 126, # 22 p. 5706 - 5709,4
反应条件
zinc(II) chloride T=180°C;
参考文献
Spaeth; Lederer
Chemische Berichte, 1930 , vol. 63, p. 2102,2106
