(E)-3-(1,3-苯并二氧戊环-5-基)丙烯酸乙酯合成路线 （共 33 条）
反应条件
1: With Verkade’s superbase in tetrahydrofuran
T=20°C; Peterson olefination; 24 h; Inert atmosphere;
2: With hydrogenchloride in tetrahydrofuran; water
T=20°C; Peterson olefination; 1 h; Inert atmosphere; stereoselective reaction;
参考文献
Wadhwa, Kuldeep; Verkade, John G.
Journal of Organic Chemistry, 2009 , vol. 74, # 11 p. 4368 - 4371
反应条件
copper(l) iodide; triphenylphosphine in tetrahydrofuran
T=60°C; 4 h; Inert atmosphere; optical yield given as percent dediastereoselective reaction;
参考文献
Lebel, Helene; Davi, Michael
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 14-15 p. 2352 - 2358
反应条件
poly{styrene-co-[4-(N-methyl-N-vinylbenzyl-amino)pyridine]-co-[1-phenyl-3-(4-vinylbenzyl)piperazine]} in N,N-dimethyl-formamide
T=50°C; decarboxylative Doebner-Knoevenagel condensation reaction; optical yield given as percent destereoselective reaction;
参考文献
Lu, Jinni; Toy, Patrick H.
Synlett, 2011 , # 12 p. 1723 - 1726
反应条件
sodium hydrogencarbonate; L-proline in water
T=100°C; Wittig reaction; air; stereoselective reaction;
参考文献
McNulty, James; McLeod, David
Chemistry - A European Journal, 2011 , vol. 17, # 32 p. 8794 - 8798
反应条件
[Ru(tricyclohexylphosphine)Cl2(CHC6H4O(i-Pr))] in 1,2-dichloro-ethane
T=70°C; Cross Metathesis; Schlenk techniqueInert atmosphereGlovebox;
参考文献
Lummiss, Justin A. M.; Oliveira, Kelley C.; Pranckevicius, Alexandre M. T.; Santos, Alexandra G.; Dos Santos, Eduardo N.; Fogg, Deryn E.
Journal of the American Chemical Society, 2012 , vol. 134, # 46 p. 18889 - 18891
反应条件
2,3-dicyano-5,6-dichloro-p-benzoquinone in toluene
T=110°C; Microwave irradiationDean-Stark;
参考文献
Sharma, Upendra K.; Sood, Swati; Sharma, Nandini; Rahi, Praveen; Kumar, Rakesh; Sinha, Arun K.; Gulati, Arvind
Medicinal Chemistry Research, 2013 , vol. 22, # 11 p. 5129 - 5140
反应条件
tributylphosphine; tetrakis(triphenylphosphine) palladium(0)
T=110°C; 24 h; Yield given. Yields of byproduct given;
参考文献
Shen, Yanchang; Zhou, Yuefen
Tetrahedron Letters, 1991 , vol. 32, # 4 p. 513 - 514
反应条件
1: With phosphonic acid,diphenyl ester in tetrahydrofuran
T=20°C; 0.5 h; Inert atmosphere;
2: in tetrahydrofuran
T=50°C; 5 h; Inert atmosphere;
参考文献
Cui, Hua; Li, Ying; Zhang, Songlin
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 14 p. 2862 - 2869
反应条件
oxygen in toluene
T=110°C; one-pot alcohol oxidation-Wittig reaction; 24 h;
参考文献
Lee, Eun Young; Kim, Youngkwon; Lee, Jae Sung; Park, Jaiwook
European Journal of Organic Chemistry, 2009 , # 18 p. 2943 - 2946
反应条件
hollandite in toluene
T=110°C; Wittig Olefination; 4 h; Catalytic behavior; diastereoselective reaction;
参考文献
Kona, Jagadeswara R.; King'Ondu, Cecil K.; Howell, Amy R.; Suib, Steven L.
ChemCatChem, 2014 , vol. 6, # 3 p. 749 - 752
