9H-吡啶并[2,3-b]吲哚合成路线 （共 33 条）
反应条件
1: 90 percent / t-BuONa; 1,1'-bis(diphenylphosphino)ferrocine / Pd2(dba)3 / toluene / 17 h / 100 °C 2: 31 percent / Na2CO3 / Pd(OAc)2 / dimethylformamide / 67 h / Heating View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 11 p. 1505 - 1510
反应条件
1: 1) lithium diisopropylamide, 2) I2, 3) H2O / 1) THF, -75 deg C, 4 h, 2) THF, -75 deg C, 1 h, 3) THF, -75 to 0 deg C 2: 96 percent / K2CO3 / Pd(PPh3)4 / ethanol; toluene / 48 h / Heating 3: 82 percent / pyridinium chloride / 0.25 h View Scheme
参考文献
Tetrahedron, , vol. 49, # 1 p. 49 - 64
反应条件
1: 1) lithium diisopropylamide, 2) I2, 3) H2O / 1) THF, -75 deg C, 4 h, 2) THF, -75 deg C, 1 h, 3) THF, -75 to 0 deg C 2: 99 percent / K2CO3 / Pd(PPh3)4 / ethanol; toluene / 48 h / Heating 3: 82 percent / pyridinium chloride / 0.25 h / Heating; cyclization of various o-pivaloylaminophenyl-o'-halopyridines View Scheme
参考文献
Tetrahedron, , vol. 49, # 1 p. 49 - 64
反应条件
1: 96 percent / K2CO3 / Pd(PPh3)4 / ethanol; toluene / 48 h / Heating 2: 82 percent / pyridinium chloride / 0.25 h View Scheme
参考文献
Tetrahedron, , vol. 49, # 1 p. 49 - 64
反应条件
1: 99 percent / K2CO3 / Pd(PPh3)4 / ethanol; toluene / 48 h / Heating 2: 82 percent / pyridinium chloride / 0.25 h / Heating; cyclization of various o-pivaloylaminophenyl-o'-halopyridines View Scheme
参考文献
Tetrahedron, , vol. 49, # 1 p. 49 - 64
反应条件
palladium on activated charcoal; diphenylether; biphenyl
参考文献
CH184474 , ;
Journal of the American Chemical Society, , vol. 81, p. 740,742
反应条件
pyridine hydrochloride 0.25 h;
参考文献
Tetrahedron, , vol. 49, # 1 p. 49 - 64
反应条件
1: n-butyllithium / tetrahydrofuran; hexane / 0 - 20 °C 2: 1,2-dichloro-benzene / 3 h / 240 °C / |Sealed tube; |Microwave irradiation View Scheme
参考文献
Organic Letters, , vol. 15, # 24 p. 6306 - 6308
反应条件
1: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 16 h / 20 °C 2: n-butyllithium / tetrahydrofuran; hexane / 0 - 20 °C 3: 1,2-dichloro-benzene / 3 h / 240 °C / |Sealed tube; |Microwave irradiation View Scheme
参考文献
Organic Letters, , vol. 15, # 24 p. 6306 - 6308
反应条件
1: 30 percent / 0.17 h / 180 °C / microwave irradiation 2: 34 percent / H4P2O7 / 0.01 h / 170 °C / microwave irradiation View Scheme
参考文献
Organic Letters, , vol. 8, # 3 p. 415 - 418
