(7CI,8CI)-m-(对甲苯)-苯甲醚合成路线 （共 44 条）
反应条件
potassium phosphate; 3-(2,6-diisopropylphenyl)-1-(2-diphenylphosphanylbenzyl)-3H-imidazol-1-ium chloride; bis(η3-allyl-μ-chloropalladium(II)) in 1,4-dioxane
T=80°C; Suzuki cross-coupling; 12 h;
参考文献
Wang, Ai-E.; Zhong, Jun; Xie, Jian-Hua; Li, Kai; Zhou, Qi-Lin
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 6 p. 595 - 598
反应条件
Pd2Cl2(micro;-Cl)2(PPh3)2; potassium carbonate in 1,4-dioxane
T=100°C; 9 h; Inert atmosphere;
参考文献
Chaudhari, Kamal R.; Wadawale, Amey P.; Jain, Vimal K.
Journal of Organometallic Chemistry, 2012 , vol. 698, p. 15 - 21
反应条件
potassium hydroxide in methanol
T=50°C; Suzuki coupling; 5 h;
参考文献
Tanaka, Shinya; Kaneko, Tetsuro; Asao, Naoki; Yamamoto, Yoshinori; Chen, Mingwei; Zhang, Wei; Inoue, Akihisa
Chemical Communications, 2011 , vol. 47, # 21 p. 5985 - 5987
反应条件
1: p-toluidine With tert.-butylnitrite; acetic acid in N,N-dimethyl-formamide
T=20°C; 0.0833333 h; Inert atmosphere;
2: dihydroxy-(3-methoxyphenyl)borane With tris-(dibenzylideneacetone)dipalladium(0); trifuran-2-yl-phosphane in N,N-dimethyl-formamide
T=90°C; 10 h; Inert atmosphere;
参考文献
Mo, Fanyang; Qiu, Di; Jiang, Yubo; Zhang, Yan; Wang, Jianbo
Tetrahedron Letters, 2011 , vol. 52, # 4 p. 518 - 522
反应条件
1: dihydroxy-(3-methoxyphenyl)borane With iodine; potassium carbonate in acetonitrile
T=80°C; 12 h; Inert atmosphereSchlenk techniqueSealed tube;
2: p-methylphenylboronic acid With palladium diacetate in acetonitrile
T=80°C; Suzuki Coupling; 14 h; Inert atmosphereSchlenk techniqueSealed tube;
参考文献
Niu, Liting; Zhang, Hao; Yang, Haijun; Fu, Hua
Synlett, 2014 , vol. 25, # 7 art. no. 691, p. 995 - 1000
反应条件
sodium t-butanolate; (N,N'-bis(2,6-di(i-Pr)phenyl)imidazol-2-ylidene)Pd(allyl)Cl in 1,4-dioxane
T=60°C; Suzuki-Miyaura cross-coupling; 3 h;
参考文献
Navarro, Oscar; Kaur, Harneet; Mahjoor, Parisa; Nolan, Steven P.
Journal of Organic Chemistry, 2004 , vol. 69, # 9 p. 3173 - 3180
反应条件
potassium phosphate; NiCl2((PPh3)P)2 in toluene
T=80°C; Substitution; 2 h; Product distribution; Further Variations:CatalystsReagentsSolventsreaction time;
参考文献
Inada, Kaoru; Miyaura, Norio
Tetrahedron, 2000 , vol. 56, # 44 p. 8657 - 8660
反应条件
palladium diacetate in water; N,N-dimethyl-formamide
T=20°C; 5 h;
参考文献
Yamamoto, Yasunori; Takizawa, Miho; Yu, Xiao-Qiang; Miyaura, Norio
Angewandte Chemie - International Edition, 2008 , vol. 47, # 5 p. 928 - 931
反应条件
bathophenanthroline; sodium t-butanolate
T=178°C; 6 h; Inert atmosphere;
参考文献
Shirakawa, Eiji; Itoh, Ken-Ichi; Higashino, Tomohiro; Hayashi, Tamio
Journal of the American Chemical Society, 2010 , vol. 132, # 44 p. 15537 - 15539
反应条件
potassium fluoride; bis(η3-allyl-μ-chloropalladium(II)) in N,N-dimethyl-formamide
T=80°C; 9 h;
参考文献
Hatanaka, Yasuo; Fukushima, Satoshi; Hiyama, Tamejiro
Chemistry Letters, 1989 , p. 1711 - 1714
Title/Abstract Full Text Show Details
Hatanaka, Yasuo; Goda, Ken-ichi; Okahara, Yoshinori; Hiyama, Tamejiro
Tetrahedron, 1994 , vol. 50, # 28 p. 8301 - 8316
