(7CI,8CI)-m-(对甲苯)-苯甲醚合成路线 （共 44 条）
反应条件
1: SbF3
2: 83 percent / KF / (η3-C3H5PdCl)2 / dimethylformamide / 9 h / 80 °C
View Scheme
参考文献
Hatanaka, Yasuo; Fukushima, Satoshi; Hiyama, Tamejiro
Chemistry Letters, 1989 , p. 1711 - 1714
反应条件
tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran
T=25°C; Negishi cross-coupling; 72 h; Inert atmosphere;
参考文献
Dong, Zhi-Bing; Manolikakes, Georg; Shi, Lei; Knochel, Paul; Mayr, Herbert
Chemistry - A European Journal, 2010 , vol. 16, # 1 p. 248 - 253
反应条件
tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran
T=25°C; Negishi cross-coupling; 96 h; Inert atmosphere;
参考文献
Dong, Zhi-Bing; Manolikakes, Georg; Shi, Lei; Knochel, Paul; Mayr, Herbert
Chemistry - A European Journal, 2010 , vol. 16, # 1 p. 248 - 253
反应条件
1: dichloromethane / 4 h / 20 °C / Inert atmosphere
2: Ni(PCy3)2Cl2 / tetrahydrofuran; 1-methyl-pyrrolidin-2-one / 8 h / 90 °C / Inert atmosphere
View Scheme
参考文献
Xie, Lan-Gui; Wang, Zhong-Xia
Angewandte Chemie - International Edition, 2011 , vol. 50, # 21 p. 4901 - 4904
反应条件
1: palladium diacetate; sodium peroxodisulphate
2: bis(1,5-cyclooctadiene)nickel (0); tri-cyclo-hexyl-phosphine; hydrogen; trimethylaluminum / toluene / 24 h / 130 °C / 750.08 Torr / |Schlenk technique
View Scheme
参考文献
Patra, Tuhin; Agasti, Soumitra; Modak, Atanu; Maiti, Debabrata
Chemical Communications, 2013 , vol. 49, # 75 p. 8362 - 8364
反应条件
potassium tetrachloropalladate; cesium fluoride
T=70°C; Suzuki coupling; 3 h; Inert atmosphere;
参考文献
Bej, Ansuman; Srimani, Dipankar; Sarkar, Amitabha
Green Chemistry, 2012 , vol. 14, # 3 p. 661 - 667
反应条件
iron(III) triphenantroline chloride; potassium tert-butylate
T=100°C; 24 h; Inert atmosphere; Overall yield = 65 percent; Overall yield = 64 mg;
参考文献
Huang, Yuxing; Moret, Marc-Etienne; Klein Gebbink, Robertus J. M.
European Journal of Organic Chemistry, 2014 , vol. 2014, # 18 p. 3788 - 3793
反应条件
bathophenanthroline; sodium t-butanolate
T=172°C; 12 h; Inert atmosphere;
参考文献
Shirakawa, Eiji; Itoh, Ken-Ichi; Higashino, Tomohiro; Hayashi, Tamio
Journal of the American Chemical Society, 2010 , vol. 132, # 44 p. 15537 - 15539
反应条件
HCN(CH2C(O)NHC6H5)CHCHN(CH2C6H5)(1+)*Cl(1-)=(HCN(CH2C(O)NHC6H5)CHCHN(CH2C6H5))Cl; potassium tert-butylate
T=20 - 100°C; 24 h; Schlenk techniqueInert atmosphereGreen chemistry; Overall yield = 62 percentSpectr.; regioselective reaction;
参考文献
Ghosh, Debalina; Lee, Jhen-Yi; Liu, Chian-Yu; Chiang, Yen-Hsin; Lee, Hon Man
Advanced Synthesis and Catalysis, 2014 , vol. 356, # 2-3 p. 406 - 410
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; potassium phosphate; n-butyllithium; 1,1'-bis(diphenylphosphanyl)ferrocenenickel(II) chloride; potassium iodide
1.) toluene, room temperature, 30 min, 2.) toluene, 80 deg C, 16 h; Yield given. Multistep reaction;
参考文献
Ueda, Masato; Saitoh, Atsushi; Oh-tani, Saori; Miyaura, Norio
Tetrahedron, 1998 , vol. 54, # 43 p. 13079 - 13086
