苯并[b]噻吩-3-基乙酸酯合成路线 （共 34 条）
反应条件
hydrogenchloride in ethanol; water 3 h;
参考文献
Gorlitzer; Vogt
Archiv der Pharmazie, 1990 , vol. 323, # 10 p. 847 - 852
反应条件
1: N,N-diethyl-2-methylsulfanylbenzamide With lithium diisopropyl amide in tetrahydrofuran
T=-78 - 20°C;
2: acetyl chloride With sodium hydride in tetrahydrofuran
T=20°C;
参考文献
Pradhan, Tarun Kanti; De, Asish
Tetrahedron Letters, 2005 , vol. 46, # 9 p. 1493 - 1495
反应条件
sodium hydride in tetrahydrofuran
T=20°C; 10 h;
参考文献
Pradhan, Tarun Kanti; De, Asish; Mortier, Jacques
Tetrahedron, 2005 , vol. 61, # 38 p. 9007 - 9017
参考文献
McClelland; D'Silva
Journal of the Chemical Society, 1931 , p. 2972,2975
Full Text Show Details
v. Auwers; Thies
Chemische Berichte, 1920 , vol. 53, p. 2296
Full Text Show Details
Friedlaender
Justus Liebigs Annalen der Chemie, 1907 , vol. 351, p. 413
反应条件
1: s-BuLi; TMEDA / tetrahydrofuran
2: LDA / tetrahydrofuran / -78 - 20 °C
3: 89 percent / NaH / tetrahydrofuran / 10 h / 20 °C
View Scheme
参考文献
Pradhan, Tarun Kanti; De, Asish; Mortier, Jacques
Tetrahedron, 2005 , vol. 61, # 38 p. 9007 - 9017
反应条件
1: LDA / tetrahydrofuran / -78 - 20 °C
2: 89 percent / NaH / tetrahydrofuran / 10 h / 20 °C
View Scheme
参考文献
Pradhan, Tarun Kanti; De, Asish; Mortier, Jacques
Tetrahedron, 2005 , vol. 61, # 38 p. 9007 - 9017
反应条件
1.1: SOCl2 / benzene / Heating
1.2: benzene / 20 °C
2.1: s-BuLi; TMEDA / tetrahydrofuran
3.1: LDA / tetrahydrofuran / -78 - 20 °C
4.1: 89 percent / NaH / tetrahydrofuran / 10 h / 20 °C
View Scheme
参考文献
Pradhan, Tarun Kanti; De, Asish; Mortier, Jacques
Tetrahedron, 2005 , vol. 61, # 38 p. 9007 - 9017
反应条件
1.1: SOCl2 / benzene / Heating
1.2: benzene / 20 °C
2.1: LDA / tetrahydrofuran / -78 - 20 °C
3.1: 89 percent / NaH / tetrahydrofuran / 10 h / 20 °C
View Scheme
参考文献
Pradhan, Tarun Kanti; De, Asish; Mortier, Jacques
Tetrahedron, 2005 , vol. 61, # 38 p. 9007 - 9017
反应条件
potassium acetate
T=120°C;
参考文献
D'Silva; McClelland
Journal of the Chemical Society, 1932 , p. 2883,2886
反应条件
potassium acetate
T=125°C;
参考文献
D'Silva; McClelland
Journal of the Chemical Society, 1932 , p. 2883,2886
Full Text Show Details
Bartlett; McClelland
Journal of the Chemical Society, 1934 , p. 818,820
