1,3-二甲基-1,3-二氢-2H-吲哚-2-酮合成路线 （共 38 条）
反应条件
acetic acid; zinc
Heating;
参考文献
Huang, Audris; Kodanko, Jeremy J.; Overman, Larry E.
Journal of the American Chemical Society, 2004 , vol. 126, # 43 p. 14043 - 14053
反应条件
benzene
Erhitzen des Reaktionsprodukts mit Aluminiumchlorid;
参考文献
Julian et al.
Journal of the American Chemical Society, 1934 , vol. 56, p. 1797,1800
反应条件
1: 91 percent / Et3N / CH2Cl2 / 6 h / 20 °C
2: 8 percent / PCy3; Pd(OAc)2; NaO-t-Bu / dioxane / 24 h / 70 °C
View Scheme
参考文献
Lee; Hartwig
Journal of Organic Chemistry, 2001 , vol. 66, # 10 p. 3402 - 3415
反应条件
2: NaH / dimethylsulfoxide
3: 67 percent / n-Bu3SnH, AIBN / toluene / 24 h / Heating
View Scheme
参考文献
Bowman, W. Russell; Heaney, Harry; Jordan, Benjamin M.
Tetrahedron Letters, 1988 , vol. 29, # 50 p. 6657 - 6660
反应条件
1: NaH / dimethylsulfoxide
2: 67 percent / n-Bu3SnH, AIBN / toluene / 24 h / Heating
View Scheme
参考文献
Bowman, W. Russell; Heaney, Harry; Jordan, Benjamin M.
Tetrahedron Letters, 1988 , vol. 29, # 50 p. 6657 - 6660
反应条件
1: 87 percent / NaH / tetrahydrofuran / Ambient temperature
2: 79 percent / tri-n-butylstannane, AIBN / toluene / Heating
View Scheme
参考文献
Jones, Keith; Thompson, Mervyn; Wright, Colin
Journal of the Chemical Society, Chemical Communications, 1986 , # 2 p. 115 - 116
反应条件
1: 73 percent / diethyl ether / 0 °C
2: 87 percent / NaH / tetrahydrofuran / Ambient temperature
3: 79 percent / tri-n-butylstannane, AIBN / toluene / Heating
View Scheme
参考文献
Jones, Keith; Thompson, Mervyn; Wright, Colin
Journal of the Chemical Society, Chemical Communications, 1986 , # 2 p. 115 - 116
反应条件
1.1: sodium nitrite; dipotassium peroxodisulfate / acetonitrile / 16 h / 120 °C / |Sealed tube
2.1: sodium hydroxide; disodium hydrogenphosphate / methanol / 1 h
2.2: 1 h / 20 °C
View Scheme
参考文献
Li, Ya-Min; Wei, Xiao-Hong; Li, Xi-An; Yang, Shang-Dong
Chemical Communications, 2013 , vol. 49, # 99 p. 11701 - 11703
反应条件
1.1: sodium hydride / tetrahydrofuran / 0 - 20 °C
1.2: 0 - 20 °C
2.1: sodium nitrite; dipotassium peroxodisulfate / acetonitrile / 16 h / 120 °C / |Sealed tube
3.1: sodium hydroxide; disodium hydrogenphosphate / methanol / 1 h
3.2: 1 h / 20 °C
View Scheme
参考文献
Li, Ya-Min; Wei, Xiao-Hong; Li, Xi-An; Yang, Shang-Dong
Chemical Communications, 2013 , vol. 49, # 99 p. 11701 - 11703
反应条件
1.1: dichloromethane / 0 - 20 °C
2.1: sodium hydride / tetrahydrofuran / 0 - 20 °C
2.2: 0 - 20 °C
3.1: sodium nitrite; dipotassium peroxodisulfate / acetonitrile / 16 h / 120 °C / |Sealed tube
4.1: sodium hydroxide; disodium hydrogenphosphate / methanol / 1 h
4.2: 1 h / 20 °C
View Scheme
参考文献
Li, Ya-Min; Wei, Xiao-Hong; Li, Xi-An; Yang, Shang-Dong
Chemical Communications, 2013 , vol. 49, # 99 p. 11701 - 11703
